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Latest Adipose derived hormones Stories

2012-03-23 05:43:10

(Ivanhoe Newswire)-- A ravenous appetite may be what causes many overweight people to be obese. Researchers have found a mutation in a single gene is responsible for the inability of neurons to effectively send out appetite suppressing signals from the body to the correct area of the brain. A study suggests that there might be a way to stimulate expression of that gene to treat obesity caused by uncontrolled eating. Researchers found that a mutation in the brain-derived neurotrophic...

2011-05-04 14:40:52

Weizmann Institute scientists have added another piece to the obesity puzzle, showing how and why a certain protein that is active in a small part of the brain contributes to weight gain. This research appeared today in Cell Metabolism. Prof. Ari Elson and his team in the Institute's Molecular Genetics Department made the discovery when working with female mice that were genetically engineered to lack this protein, called protein tyrosine phosphatase epsilon (PTPe, for short). The...

2010-01-05 20:53:48

Researchers have found that even a very little bit of the fat hormone leptin goes a long way when it comes to correcting diabetes. The hormone controls the activity of a gene known as IGFBP2 in the liver, which has antidiabetic effects in animals and could have similar therapeutic effect in humans, according to a report published by Cell Press in the January issue of Cell Metabolism. The new findings confirm what some at least had already suspected: that leptin's antidiabetic effects are...

2009-08-25 11:29:20

British scientists say studying brown adipose tissue found in hibernating animals and newborn babies may lead to new ways of preventing obesity. The researchers from the University of Nottingham, led by Professor Michael Symonds, said studies have already shown brown adipose tissue -- brown fat -- in adults is reduced with obesity. Therefore, promoting BAT function could prevent or reduce obesity in some people, they said. New research, led by Symonds and his team, has shown daylight is a...

2009-01-07 18:37:32

The potential of the appetite suppressing hormone -- leptin -- may be realized after all, U.S. researchers say. The discovery of leptin, an appetite-suppressing hormone secreted by fat tissue, created great hopes for an effective treatment for obesity, but it was found the obese are unresponsive to leptin due to leptin resistance in the brain. The study, published in Cell Metabolism, found two chaperones -- 4-PBA or TUDCA -- increase leptin sensitivity as much as 10-fold and resulted in...

2009-01-07 09:19:09

The first known leptin-sensitizing agents induce mice to lose weightThe discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes dimmed when it was found that obese people are unresponsive to leptin due to development of leptin resistance in the brain. Now, researchers at Children's Hospital Boston report the first agents demonstrated to sensitize the brain to...

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2005-08-16 14:50:00

A weight control protein with a key role in the brain's ability to monitor body fat content may yield new approaches for treating obesity and type 2 diabetes, according to a new report in the August issue of Cell Metabolism. The findings in mice further suggest that particular variants of the protein SH2-B might underlie obesity in humans, the researchers said. SH2-B, which has multiple functions in cells throughout the body, keeps the brain sensitive to the fat hormone leptin, found...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.