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Latest adrenal tumor Stories

Sodium Retention And Blood Pressure Increased By Common Genetic Mutation
2012-05-30 08:43:57

Nearly 40 percent of the small adrenal tumors that cause big problems with high blood pressure share a genetic mutation that causes patients to retain too much sodium, researchers report. The study of 47 human, benign adrenal gland tumors also showed a mutation of the gene KCNJ5 is twice as likely to occur in women — 71 versus 29 percent — as it points to potential new treatments for some patients who don't respond to current hypertension regimens, said Dr. William E. Rainey,...

2011-02-18 08:11:45

(Ivanhoe Newswire) "“ Yale University researchers have identified two breakthrough genetic mutations that can trigger hypertension in up to a third of patients suffering from a common cause of severe high blood pressure. The findings are a major step in understanding the causes of high blood pressure, which affects one out of every three Americans, explained Richard Lifton, Sterling Professor and chair of the Department of Genetics, professor of internal medicine and senior author of...

2010-12-28 08:21:30

(Ivanhoe Newswire) "“ Variations of a gene are associated with a type of tumor that forms within the adrenal gland, and were found in an age group uncommon for these types of tumors. Pheochromocytomas and paragangliomas are types of tumors. Pheochromocytomas form in the adrenal gland causing it to make too much adrenaline. Pheochromocytomas can cause high blood pressure, pounding headaches, heart palpitations, flushing of the face, nausea, and vomiting. Paragangliomas are rare, usually...

2010-12-15 00:03:16

Analysis has identified variations of a gene that are associated with a type of tumor that forms within the adrenal gland, according a study in the December 15 issue of JAMA. The age group in which these variations were found are frequently excluded from genetic screening models for this type of tumor. Pheochromocytomas and paragangliomas are types of tumors. Pheochromocytomas form in the adrenal gland (gland located above the kidney) causing it to make too much adrenaline. Pheochromocytomas...

2009-09-22 13:54:11

OSI-906 in clinical trial for adrenocortical carcinoma TGen Clinical Research Services at Scottsdale Healthcare today announced the start of a clinical trial for a drug designed to combat adrenocortical carcinoma (ACC), a rare but deadly cancer that attacks the adrenal glands. TCRS is a strategic alliance between the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare. Other than surgery, the only treatment for ACC is the exacting use of a compound called mitotane, a...

2009-09-22 11:00:00

OSI-906 in clinical trial for adrenocortical carcinoma SCOTTSDALE, Ariz., Sept. 22 /PRNewswire-USNewswire/ -- TGen Clinical Research Services at Scottsdale Healthcare today announced the start of a clinical trial for a drug designed to combat adrenocortical carcinoma (ACC), a rare but deadly cancer that attacks the adrenal glands. TCRS is a strategic alliance between the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare. Other than surgery, the only treatment for...

2009-06-04 10:02:24

 At the ends of chromosome are special pieces of DNA called telomeres. Think of it as the little tip that caps off a shoelace. The telomeres send signals to the cells to let them know it's the end point, not a break that should be repaired.Over time, as cells reproduce, the telomeres become shorter and eventually no longer do their job. The cells then have a higher risk of mutating into cancer.But, a new study finds, if the telomere becomes dysfunctional at any point "“ regardless...

2008-08-30 09:00:21

By Tischler, Arthur S * Context.-Advances in genetics and gene expression profiling have led to new ways of thinking about the pathobiology of pheochromocytoma and extra-adrenal paraganglioma. These developments are concurrent with the publication and dissemination of the 2004 World Health Organization bluebook on pathology and genetics of endocrine tumors. Objective.-To summarize new information required by pathologists for effective participation in patient management and research. Data...

2008-08-30 09:00:20

By McNicol, Anne Marie * Context.-In surgical pathology practice adrenal cortical tumors are rare. However, in autopsy series adrenal cortical nodules are found frequently. These are now being identified more commonly in life when the abdomen is scanned for other disease. It is important to differentiate between benign and malignant lesions as adrenal cortical carcinoma is an aggressive tumor. Molecular genetic investigations are providing new information on both pathogenesis of adrenal...

2008-02-13 03:00:13

By Timonera, Elizabeth R Paiva, Maria Emilia; Lopes, Jose Manuel; Eloy, Catarina; van der Kwast, Theodore; Asa, Sylvia L Adenomatoid tumor and myelolipoma are benign, hormonally inactive tumors that are often incidental findings in the adrenal glands. Myelolipoma is more common than adenomatoid tumor in this location but both are rare, and as yet, the pathogenesis of both remains unclear.We report 2 cases of composite adenomatoid tumor and myelolipo-ma, incidentally found in the adrenal...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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