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Last updated on April 21, 2014 at 1:20 EDT

Latest Affinity maturation Stories

2014-02-18 08:32:37

BURNABY, BC, Feb. 18, 2014 /PRNewswire/ - Innovative Targeting Solutions Inc. (ITS) a pioneer in novel protein engineering technologies, today announced the successful application of the company's proprietary affinity maturation technology for the purposes of generating antibodies with pM affinities. These first in class antibodies are unique in that all mutations are specifically targeted to CDRs, unlike error prone PCR, somatic hypermutation or other traditional mutagenesis...

2012-12-04 08:28:39

SAN DIEGO, Dec. 4, 2012 /PRNewswire/ -- AnaptysBio, Inc., a privately-held therapeutic antibody company, today announced the publication of a novel full-length antibody scaffold, applicable to the development of highly thermostable antibodies for therapeutic and diagnostic applications, in the journal of Protein Engineering, Design & Selection (PEDS). (Logo: http://photos.prnewswire.com/prnh/20111205/SF16052LOGO) Entitled "An integrated approach to extreme...

2012-10-18 07:25:54

SAN DIEGO, Oct. 18, 2012 /PRNewswire/ -- AnaptysBio, Inc., a privately held therapeutic antibody company, today announced the issuance of Patent # 8,288,160 entitled "Activation Induced Deaminase (AID)" by the U.S. Patent and Trademark Office (USPTO). This patent, the 16(th) issuance in AnaptysBio's intellectual property portfolio, broadly covers the use of in vitro somatic hypermutation (SHM) in eukaryotic cells for the discovery and optimization of antibodies. Previously...

2011-12-05 14:00:00

SAN DIEGO, Calif., Dec. 5, 2011 /PRNewswire/ -- AnaptysBio, Inc., a privately-held therapeutic antibody company, today announced the publication of original research describing the discovery of novel fully-human antibodies against human nerve growth factor (NGF) using AnaptysBio's SHM-XEL(TM) platform in the Proceedings of the National Academy of Sciences (PNAS). (Logo: http://photos.prnewswire.com/prnh/20111205/SF16052LOGO) Entitled "Coupling Mammalian Cell Surface Display...