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Last updated on April 18, 2014 at 13:23 EDT

Latest African trypanosomiasis Stories

2014-01-03 15:54:30

Caught in the act! Researchers from the University of Bristol have observed mating for the first time in the microbes responsible for African sleeping sickness. This tropical disease is caused by trypanosomes, single-celled parasites that are found in the blood of those afflicted. The Bristol team were able to see what the trypanosomes were getting up to inside the tsetse flies that carry the disease by using fluorescent markers [see image – link below]. The microscopic beasts were seen...

Innovative Approach Could Ultimately End Sleeping Sickness Disease
2013-10-03 12:29:37

Oregon State University A tag team of two bacteria, one of them genetically modified, has a good chance to reduce or even eliminate the deadly disease African trypanosomiasis, or sleeping sickness, researchers at Oregon State University conclude in a recent mathematical modeling study. African trypanosomiasis, caused by a parasite carried by the tsetse fly, infects 30,000 people in sub-Saharan Africa each year and is almost always fatal without treatment. In a 2008 epidemic, 48,000...

2013-08-19 08:29:04

REHOVOT, Israel, August 19, 2013 /PRNewswire/ -- D-Pharm Ltd., (TASE: DPRM) announced today on-line publication of promising results with its drug candidates, DP-460 and DP-b99, in models of human African trypanosomiasis (HAT) and malaria. These exciting results, demonstrate the potential of D-Pharm's proprietary platform technology, Membrane Active Chelators (MAC), to address these devastating parasitic diseases. Malaria and HAT are a major world health problem with...

2013-02-27 11:10:53

Screening method created to expedite the development of new drugs in the fight against tropical diseases such as malaria and African sleeping sickness A novel tool exploits baker's yeast to expedite the development of new drugs to fight multiple tropical diseases, including malaria, schistosomiasis, and African sleeping sickness. The unique screening method uses yeasts which have been genetically engineered to express parasite and human proteins to identify chemical compounds that target...

2012-05-22 21:28:08

Lies Van Nieuwenhove, researcher at the Antwerp Institute of Tropical Medicine, has produced proteins imitating typical parts of the sleeping sickness parasite. They can be used in more efficient diagnostic tests, without the need for culturing dangerous parasites. Each year many thousands of Africans contract sleeping sickness. The cause is a unicellular parasite, a trypanosome, which is transmitted by the bite of tsetse flies. First the parasite multiplies in blood and lymph, while...

2012-05-21 23:54:22

DNDi welcomes World Health Organization expert recommendations to begin negotiations for an R&D convention at the World Health Assembly After a decade-long process of analysis and deliberations on ways to better address the health needs of developing countries, a recently released report of the Consultative Expert Working Group on Research and Development: Financing and Coordination (CEWG) will be discussed this week at the 65th World Health Assembly (agenda item 13.14). The Drugs for...

MSU Plan Would Control Deadly Tsetse Fly
2012-05-07 09:41:04

For the first time, scientists have created a satellite-guided plan to effectively control the tsetse fly — an African killer that spreads “sleeping sickness” disease among humans and animals and wipes out $4.5 billion in livestock every year. Michigan State University researchers developed the plan using a decade´s worth of NASA satellite images of Kenyan landscape and by monitoring tsetse movement. With unprecedented precision, the plan can tell where and when to...

2012-01-30 05:05:00

GENEVA, Jan. 30, 2012 /PRNewswire/ -- The Drugs for Neglected Diseases initiative (DNDi) and Abbott (NYSE: ABT) have signed a four-year joint research and non-exclusive licensing agreement to undertake research on new treatments for several of the world's most neglected tropical diseases, including Chagas disease, helminth infections, leishmaniasis and sleeping sickness. Through this collaboration, DNDi and Abbott scientists will focus initial efforts on discovering and advancing novel...

2012-01-26 02:11:22

Research led by scientists at the London School of Hygiene & Tropical Medicine has exploited a revolutionary genetic technique to discover how human African Trypanosomiasis (HAT) drugs target the parasite which causes the disease. The new knowledge could help lead to the development of better treatments for the tens of thousands of people in sub-Saharan Africa who are affected each year. The findings, published in Nature, are based on the simultaneous analysis of thousands of genes and...

2011-09-07 11:12:51

A new study published in the open-access journal PLoS Neglected Tropical Diseases on September 6th presents a key advance in developing a safer cure for sleeping sickness. Led by Professor Peter Kennedy, researchers at the University of Glasgow's Institute for Infection, Immunology and Inflammation have created a version of the drug most commonly used to treat sleeping sickness which can be administered orally in pill form. Sleeping sickness — or human African trypanosomiasis (HAT)...