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Latest Alan Saltiel Stories

Old Asthma Drug Provides Benefits For Treating Diabetes, Obesity
2013-02-11 07:23:38

Lawrence LeBlond for redOrbit.com - Your Universe Online A drug that is normally prescribed for asthma patients is breathing new life as a potential treatment option for people who suffer from diabetes and obesity. The drug, amlexanox, was demonstrated to reverse obesity, diabetes and fatty liver in mice in a new study, published this week in the journal Nature Medicine. The finding comes from the research lab of Alan Saltiel, the Mary Sue Coleman director of the Life Sciences Institute...

2009-09-03 15:22:07

University of Michigan researchers have identified a gene that acts as a master switch to control obesity in mice. When the switch is turned off, even high-fat-diet mice remain thin. Deleting the gene, called IKKE, also appears to protect mice against conditions that, in humans, lead to Type 2 diabetes, which is associated with obesity and is on the rise among Americans, including children and adolescents. If follow-up studies show that IKKE is tied to obesity in humans, the gene and the...

2005-09-13 11:35:00

A new study reveals critical molecular events in the origin of fat cells. The findings are central to understanding chronic diseases, such as obesity and diabetes, as fat cells produce hormones critical for metabolic control, the researchers said. The study finds that a hormonal cocktail routinely used in the lab induces a key genetic switch in the transition from fat-cell precursors to full-blown fat, researchers at University of Michigan Life Sciences Institute report in the September Cell...


Word of the Day
abrosia
  • Wasting away as a result of abstinence from food.
The word 'abrosia' comes from a Greek roots meaning 'not' and 'eating'.