Latest Albert R. La Spada Stories
Pair helps remove and prevent misfolding of proteins that cause neurodegeneration In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critical to clearing away misfolded proteins that accumulate and cause the progressive, deadly neurodegeneration of Huntington's disease (HD). The findings explain a fundamental aspect of how HD wreaks havoc...
A team of scientists from Japan and the University of California, San Diego School of Medicine have created a new mouse model that confirms that mutations of a protein called beta-synuclein promote neurodegeneration. The discovery creates a potential new target for developing treatments of diseases like Parkinson's and Alzheimer's. The work is published in today's issue of Nature Communications. Lead author is Makoto Hashimoto of the Division of Chemistry and Metabolism, Tokyo Metropolitan...
- A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
- A gentle breeze; a waft; a breath.
- Any rumor that engages general attention.
- A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
- To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
- To breathe in or as in sleep.
- To utter in a whining or monotonous tone.