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Last updated on April 21, 2014 at 7:52 EDT

Latest alcoholic liver disease Stories

2014-04-14 12:28:15

Exciting new data presented today at the International Liver Congress™ 2014 shows that the gut microbiota has a potential role in the development of alcoholic liver disease (ALD). Though an early stage animal model, the French study highlights the possibility of preventing ALD with faecal microbiota transplantation – the engrafting of new microbiota, usually through administering human faecal material from a healthy donor into the colon of a recipient. In the study, two groups of...

2014-01-20 09:51:05

Researchers from the University of Notre Dame and the Indiana University School of Medicine have revealed a putative role for the circadian clock in the liver in the development of alcohol-induced hepatic steatosis, or fatty liver disease. Hepatic steatosis is the abnormal accumulation of fats in the cells of the liver, and is linked to disturbed control of fat metabolism. Alcohol-induced liver steatosis is produced by excessive alcohol consumption and is linked to hepatitis, or...

2013-11-11 13:14:01

More damage seen when FOXO3 suppressed, according to report in The American Journal of Pathology New data suggest that the transcription factor FOXO3 may protect against alcohol-induced liver injury. Researchers determined that alcohol given to mice deficient in FOXO3 caused severe liver injury resembling human alcoholic hepatitis. Further they found that although hepatitis C virus (HCV) and alcohol independently activated FOXO3, in combination they suppressed FOXO3, reduced expression of...

Binge Drinking On The Weekend Has Long-Term Consequences
2013-05-02 06:55:21

redOrbit Staff & Wire Reports - Your Universe Online A hangover might not be the only unfriendly reminder of a weekend of heavy alcohol consumption, according to a new University of Missouri study that has linked binge drinking with an increased risk of liver disease as well as a number of other potential health issues. “In our research, we found that binge drinking has a profound effect on the liver in various modes of alcohol exposure,” Shivendra Shukla, corresponding...

2013-04-06 23:02:34

Bel Marra Health, who offers high-quality, specially formulated vitamins and nutritional supplements, is reporting on new research that says the value of liver cancer screening in patients with alcoholic cirrhosis might be questionable. Toronto, ON (PRWEB) April 06, 2013 Bel Marra Health, who offers high-quality, specially formulated vitamins and nutritional supplements, is reporting on new research that says the value of liver cancer screening in patients with alcoholic cirrhosis might be...

2012-07-04 22:46:49

Scientists at Texas Biomed have developed the laboratory opossum as a new animal model to study the most common liver disease in the nation — afflicting up to 15 million Americans — and for which there is no cure. The condition, nonalcoholic steatohepatitis (NASH), resembles alcoholic liver disease, but occurs in people who drink little or no alcohol. The major feature of NASH is accumulation of fat in the liver, along with inflammation and functional damage. Most people with...

2012-05-07 20:35:33

Research with mice reveals possible strategy to reverse fibrosis in liver and other organs An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, report that significant numbers of myofibroblasts — cells that produce the fibrous scarring in chronic liver injury — revert to an inactive phenotype as the liver heals. The discovery in mouse models could ultimately help lead to new human therapies for reversing fibrosis...

2012-04-19 19:52:08

Hepatitis B virus guidelines revised EASL today announced the publication of a new clinical practice guideline (CPG) in the area of Alcoholic Liver Disease (ALD), bringing the number of CPGs published to date to eight. ALD, a result of regular and heavy drinking, is the leading cause of liver disease in eastern and western Europe. Europe has the highest alcohol consumption in the world, at 12.18 liters of pure alcohol per person per year. Despite this there has been limited research...

2011-12-06 22:52:40

It has been widely observed that only a small percentage of alcoholics develop cirrhosis of the liver, the most advanced form of alcoholic liver disease (ALD); the reason why all alcoholics do not develop such disease is not known. The present study from Spain, that includes original work and a meta-analysis, evaluates whether genetic polymorphisms that determine levels of glutathione-S-transferases (GST) relate to the risk of developing ALD among alcoholics. Alcoholics with certain genetic...

2011-05-03 13:19:48

An antioxidant may prevent damage to the liver caused by excessive alcohol, according to new research from the University of Alabama at Birmingham. The findings, published online April 21, 2011, in the journal Hepatology, may point the way to treatments to reverse steatosis, or fatty deposits in the liver that can lead to cirrhosis and cancer. The research team, led by Victor Darley-Usmar, Ph.D., professor of pathology at UAB, introduced an antioxidant called mitochondria-targeted ubiquinone,...