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2013-09-16 10:36:23

Dr. David Pollock has a simple message for fellow hypertension researchers: think endothelin. In a country where better than 30 percent of adults have high blood pressure and 50-75 percent of those have salt-sensitive hypertension, he believes the powerful endothelin system, which helps the body eliminate salt, should not be essentially ignored. However, the research and clinical world focus on suppressing a better-known system, which prompts the body to hold onto salt, said Pollock,...

Stress Can Cause Some To Retain As Much Salt As Eating Fries
2012-09-07 13:47:20

When stressed, about 30 percent of blacks hold onto too much sodium, the equivalent of eating a small order of fast food French fries or a small bag of potato chips, researchers say. "This response pattern puts you under a greater blood pressure load over the course of the day and probably throughout the night as well, increasing your risk of cardiovascular disease," said Dr. Gregory Harshfield, hypertension researcher at the Institute of Public and Preventive Health at Georgia Health...

Sodium Retention And Blood Pressure Increased By Common Genetic Mutation
2012-05-30 08:43:57

Nearly 40 percent of the small adrenal tumors that cause big problems with high blood pressure share a genetic mutation that causes patients to retain too much sodium, researchers report. The study of 47 human, benign adrenal gland tumors also showed a mutation of the gene KCNJ5 is twice as likely to occur in women — 71 versus 29 percent — as it points to potential new treatments for some patients who don't respond to current hypertension regimens, said Dr. William E. Rainey,...

2011-11-18 03:49:24

For people who initially survive a heart attack, a significant cause of death in the next few days is cardiac rupture -- literally, bursting of the heart wall. A new study by University of Iowa researchers pinpoints a single protein as the key player in the biochemical cascade that leads to cardiac rupture. The findings, published Nov. 13 as an Advance Online Publication (AOP) of the journal Nature Medicine, suggest that blocking the action of this protein, known as CaM kinase, may help...

2011-11-09 15:30:00

The Salt Institute asks federal agencies to reverse their anti-salt agenda to protect the American public from the well-documented risk of diabetes, stroke, and heart disease that comes with the government's dangerous LOW-salt diet. Washington, DC (PRWEB) November 09, 2011 A meta-analysis published today (Nov. 9) in the American Journal of Hypertension confirms what the Salt Institute has been warning for years: -- Low-sodium diets trigger a negative chain reaction in the body that...

2011-09-22 21:30:32

Emergence of ENaC, sodium pump coincides with first appearance of multi-celled creatures Maintaining fluid balance in the body is essential to survival, from the tiniest protozoa to the mightiest of mammals. By researching recent genomic data, Swiss researchers have found genetic evidence that links this intricate process to a turning point in evolution. The study was led by Bernard Rossier, Professor Emeritus, University of Lausanne, along with colleagues Romain A. Studer, Emilie...

2011-09-19 21:48:16

Dietary salt intake and obesity are two important risk factors in the development of high blood pressure. Each packs its own punch, but when combined, they deliver more damage to the heart and kidneys than the sum of their individual contributions. Discovering the molecular mechanisms behind this lethal synergy has presented a challenge to scientists, but research led by Toshiro Fujita, MD, professor and chairman of the Department of Internal Medicine and chief of the Department of Nephrology...

2011-02-18 08:11:45

(Ivanhoe Newswire) "“ Yale University researchers have identified two breakthrough genetic mutations that can trigger hypertension in up to a third of patients suffering from a common cause of severe high blood pressure. The findings are a major step in understanding the causes of high blood pressure, which affects one out of every three Americans, explained Richard Lifton, Sterling Professor and chair of the Department of Genetics, professor of internal medicine and senior author of...

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2011-02-11 10:25:00

High blood pressure may in some cases be caused by benign hormone-producing tumors of the adrenal cortex. A joint Swedish-American research effort has now uncovered a genetic cause behind the occurrence of such tumors. The findings were published Feb. 10 in the journal Science. Approximately 5 percent of patients with elevated blood pressure have benign endocrine tumors in their adrenal gland. The tumors produce abnormally high levels of the hormone aldosterone (the condition is known as...

2011-01-17 22:17:53

Scientists have identified the first DNA sequence variant common in the population that is not only associated with an increased risk of heart failure, but appears to play a role in causing it. The variant, a change in a single letter of the DNA sequence, impairs channels that control kidney function. "It's not a heart gene," says Gerald W. Dorn II, MD, the Philip and Sima K. Needleman Professor of Medicine at Washington University School of Medicine in St. Louis and a lead investigator on...


Latest Aldosterone Reference Libraries

Adrenal Gland
2013-03-04 12:51:56

The adrenal glands are endocrine glands located directly on top of the kidneys. Their main function is to secrete vital hormones and steroids during times of stress, as well as govern many different bodily functions. The hormones that the adrenal glands secrete are primarily derived from amino acids or lipids. The right adrenal gland is pyramid-shaped, while the left adrenal gland is shaped like a crescent moon. They have an irregular surface configuration, are enclosed in a capsule made of...

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Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
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