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2011-08-29 20:24:39

Colchicine, when given in addition to conventional therapy, was more effective than placebo in reducing the incidence of recurrence and the persistence of symptoms of pericarditis in a randomised controlled trial. This is the first time that the efficacy of colchicine in preventing recurrent episodes of pericarditis has been demonstrated in a double-blind multicentre randomised trial. "Recurrence," said investigator Dr Massimo Imazio from the Maria Vittoria Hospital in Turin, Italy,"is the...

2011-08-26 07:00:00

Premiere Oncology today announced that it is participating in a Phase 2b/3 clinical trial of ganetespib, a novel, potent anti-cancer drug in combination with docetaxel, an approved chemotherapy drug, for the treatment of non-small cell lung cancer patients. Santa Monica, CA (PRWEB) August 26, 2011 Ganetespib is the most advanced drug candidate in a new class of anti-cancer drugs called heat shock protein (Hsp) 90 inhibitors. Hsp90 is a molecular chaperone required for the proper folding...

2011-08-25 12:04:53

Scientists at Yale University have developed the first practical method to create a compound called huperzine A in the lab. The compound, which occurs naturally in a species of moss found in China, is an enzyme inhibitor that has been used to treat Alzheimer's disease in China since the late 1990s and is sold in the U.S. as a dietary supplement to help maintain memory. Scientists believe it could also potentially combat the effects of chemical warfare agents. Until now, researchers have...

2011-08-11 12:31:00

PHILADELPHIA, Aug. 11, 2011 /PRNewswire/ -- Newly-published results from a series of colchicine safety studies provide physicians with the first evidence-based dosing guidance for colchicine when co-administered with certain commonly prescribed drugs, helping doctors and patients avoid serious and potentially life-threatening drug-drug interactions. The study results, published in a paper titled "Evidence Basis of a Novel Colchicine Dose Reduction Algorithm to Predict and Prevent...

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2011-08-02 07:07:15

New research in the FASEB Journal suggests that nicotine protects dopamine neurons in the brain, by activating the alpha-7 nicotinic receptor Bethesda, MD"”If you've ever wondered if smoking offered society any benefit, a new research report published in The FASEB Journal offers a surprising answer. Nicotine protects us from Parkinson's disease, and the discovery of how nicotine does this may lead to entirely new types of treatments for the disease. "This study raises the hope for a...

2011-07-27 14:24:50

Animal study suggests a common process for both the pleasurable and anxiety-reducing effects of nicotine Removing a protein from cells located in the brain's reward center blocks the anxiety-reducing and rewarding effects of nicotine, according to a new animal study in the July 27 issue of The Journal of Neuroscience. The findings may help researchers better understand how nicotine affects the brain. Nicotine works by binding to proteins called nicotinic receptors on the surface of brain...

2011-07-26 13:52:24

Study uncovers several compounds that inhibit cancer cell invasion, but also reveals that cancer drug paclitaxel does the opposite"”it promotes cancer metastasis. Metastasis"”the spread of cancer from the place where it first started to another place in the body"”is the most common reason that cancer treatments fail. To metastasize, some types of cancer cells rely on invadopodia, cellular membrane projections that act like feet, helping them "walk" away from the primary...

2011-07-15 00:00:37

With CanadaDrugsUnited.com, patients need not fret over the price hike of their gout drug Colchicine as medication cost will be kept reasonable and affordable. Los Angeles, CA (PRWEB) July 14, 2011 Despite the dramatic price increase for the gout drug Colchicine in the recent year, online pharmacy CanadaDrugsUnited.com is keeping the price economical and affordable for patients around the world. According to a report in 2010 by online health magazine Arthritis Today, the price of Colchicine...

2011-06-30 18:18:41

New research in the FASEB Journal suggests that activation of nicotinic receptors within the prefrontal region of the mouse brain helps establish appropriate ranking between competing motivations If you think nicotine receptors are only important to smokers trying to kick the tobacco habit, think again. New research published in the FASEB Journal (http://www.fasebj.org) suggests that these receptors also play an important role in social interaction and the ability to choose between competing...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.