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Latest Alkaloids Stories

2011-08-11 12:31:00

PHILADELPHIA, Aug. 11, 2011 /PRNewswire/ -- Newly-published results from a series of colchicine safety studies provide physicians with the first evidence-based dosing guidance for colchicine when co-administered with certain commonly prescribed drugs, helping doctors and patients avoid serious and potentially life-threatening drug-drug interactions. The study results, published in a paper titled "Evidence Basis of a Novel Colchicine Dose Reduction Algorithm to Predict and Prevent...

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2011-08-02 07:07:15

New research in the FASEB Journal suggests that nicotine protects dopamine neurons in the brain, by activating the alpha-7 nicotinic receptor Bethesda, MD"”If you've ever wondered if smoking offered society any benefit, a new research report published in The FASEB Journal offers a surprising answer. Nicotine protects us from Parkinson's disease, and the discovery of how nicotine does this may lead to entirely new types of treatments for the disease. "This study raises the hope for a...

2011-07-27 14:24:50

Animal study suggests a common process for both the pleasurable and anxiety-reducing effects of nicotine Removing a protein from cells located in the brain's reward center blocks the anxiety-reducing and rewarding effects of nicotine, according to a new animal study in the July 27 issue of The Journal of Neuroscience. The findings may help researchers better understand how nicotine affects the brain. Nicotine works by binding to proteins called nicotinic receptors on the surface of brain...

2011-07-26 13:52:24

Study uncovers several compounds that inhibit cancer cell invasion, but also reveals that cancer drug paclitaxel does the opposite"”it promotes cancer metastasis. Metastasis"”the spread of cancer from the place where it first started to another place in the body"”is the most common reason that cancer treatments fail. To metastasize, some types of cancer cells rely on invadopodia, cellular membrane projections that act like feet, helping them "walk" away from the primary...

2011-07-15 00:00:37

With CanadaDrugsUnited.com, patients need not fret over the price hike of their gout drug Colchicine as medication cost will be kept reasonable and affordable. Los Angeles, CA (PRWEB) July 14, 2011 Despite the dramatic price increase for the gout drug Colchicine in the recent year, online pharmacy CanadaDrugsUnited.com is keeping the price economical and affordable for patients around the world. According to a report in 2010 by online health magazine Arthritis Today, the price of Colchicine...

2011-06-30 18:18:41

New research in the FASEB Journal suggests that activation of nicotinic receptors within the prefrontal region of the mouse brain helps establish appropriate ranking between competing motivations If you think nicotine receptors are only important to smokers trying to kick the tobacco habit, think again. New research published in the FASEB Journal (http://www.fasebj.org) suggests that these receptors also play an important role in social interaction and the ability to choose between competing...

2011-06-20 23:52:09

LMU chemists design a route for synthesis of loline alkaloids LMU chemists led by Professor Dirk Trauner have developed a concise and efficient method for the synthesis of the alkaloid loline and related compounds. Loline alkaloids are a biologically interesting group of natural products, which have unusual physicochemical and pharmacological characteristics, but are as of yet poorly understood. They are produced by fungal symbionts that infect weeds and forage grasses, and act as deterrents...

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2011-06-10 05:31:00

A team of scientists led by Yale School of Medicine has discovered a brain mechanism that explains how nicotine suppresses appetite "“ findings that could someday help develop medications to help people quit smoking without gaining weight.  While previous research shows the average weight gain after quitting smoking is less than 10 pounds, fear of gaining weight can discourage some people from kicking the habit. The current study revealed that a specific subclass of brain...

2011-06-06 16:39:00

PITTSBURGH, June 6, 2011 /PRNewswire/ -- Dr. Bradley Monk of the Creighton University School of Medicine presented a new gynecologic cancer study at the 2011 American Society of Clinical Oncology (ASCO) Annual Symposium, June 5th in Chicago, Illinois. The study, titled, Acquired Drug Resistance in Gynecologic Cancer Detected by an In Vitro Assay, begins to answer the question of whether ChemoFx® Drug Response Marker test results taken in the primary setting can be...

2011-05-19 19:48:00

SOUTH SAN FRANCISCO, Calif., May 19, 2011 /PRNewswire/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced updated results from the Phase 2b 003-A1 study of single-agent carfilzomib, a next generation proteasome inhibitor, in patients with relapsed and refractory multiple myeloma. Carfilzomib achieved a clinical benefit rate (CBR) (minimal response or greater) in the study population of 37 percent with a duration of response (DOR) of 8.3 months. The primary endpoint, overall...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
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