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Latest Alpha-synuclein Stories

2013-04-26 10:24:16

A protein known to be a key player in the development of Parkinson's disease is able to enter and harm cells in the same way that viruses do, according to a Loyola University Chicago Stritch School of Medicine study. The protein is called alpha-synuclein. The study shows how, once inside a neuron, alpha synuclein breaks out of lysosomes, the digestive compartments of the cell. This is similar to how a cold virus enters a cell during infection. The finding eventually could lead to the...

2013-03-04 11:17:30

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells. The study, which published online today in the journal Nature Neuroscience, could also open up treatment possibilities for both familial Parkinson's and the more common form of Parkinson's that is not inherited. Parkinson's disease is a gradually progressing disorder of the nervous system that causes stiffness or...

Molecular Probe May Help In Understanding Parkinson's
2012-12-18 07:55:12

[ Watch the Video: Rice University Opens New Window on Parkinson´s Disease ] Lee Rannals for redOrbit.com - Your Universe Online Scientists at Rice University have found a new way to look inside living cells to see the insoluble fibrillar deposits associated with Parkinson's disease. Two laboratories at the university helped lead to the spectroscopic technique that could be a valuable tool for fighting the disease. The team wrote in the Journal of the American Chemical...

2012-07-19 02:40:57

Imaging technique offers novel way to monitor neurodegenerative disorders in live animal models of Parkinson's disease Using a two-photon microscope capable of peering deep within living tissue, researchers at the University of California, San Diego School of Medicine have found new evidence that alpha-synuclein protein build-up inside neurons causes them to not only become "leaky," but also to misfire due to calcium fluxes. The findings — the first recorded in vivo using a...

2012-06-27 22:26:20

Long-term aim is to develop new treatments to block the spread of damaged proteins in the brain Van Andel Institute announces that researchers at Lund University in Sweden have published a study detailing how Parkinson's disease spreads through the brain. Experiments in rat models uncover a process previously used to explain mad cow disease, in which misfolded proteins travel from sick to healthy cells. This model has never before been identified so clearly in a living organism, and the...

2012-06-27 07:05:57

Long-term aim is to develop new treatments to block the spread of damaged proteins in the brain Grand Rapids, Mich. (June 27, 2012) — Van Andel Institute announces that researchers at Lund University in Sweden have published a study detailing how Parkinson's disease spreads through the brain. Experiments in rat models uncover a process previously used to explain mad cow disease, in which misfolded proteins travel from sick to healthy cells. This model has never before been identified...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'