Latest Alpha-synuclein Stories
FINDINGS: Several structurally similar small molecules appear capable of protecting cells from alpha-synuclein toxicity, a hallmark of Parkinson's disease.
NEW YORK, Dec. 15 /PRNewswire-USNewswire/ -- The Michael J. Fox Foundation announced $1.7 million in funding to drive new and continuing Parkinson's research projects at the Banner Sun Health Research Institute and Mayo Clinic Arizona, sites of the Arizona Parkinson's Disease Consortium.
NEW YORK, Dec. 10 /PRNewswire-USNewswire/ -- As part of its mission to accelerate promising therapeutic targets through the development pipeline toward clinical trials and, ultimately, patient care, The Michael J.
Both genetic and pathologic data indicate a role for the neuronal protein alpha-synuclein in Parkinson disease.
Parkinson's disease is well-known for impairing movement and causing tremors, but many patients also develop other serious problems, including sleep disturbances and significant losses in cognitive function known as dementia.
Accumulation of the synaptic protein alpha-synuclein, resulting in the formation of aggregates called Lewy bodies in the brain, is a hallmark of Parkinson's and other related neurodegenerative diseases.
Researchers funded by the National Institutes of Health have turned simple baker's yeast into a virtual army of medicinal chemists capable of rapidly searching for drugs to treat Parkinson's disease.
In a study that reveals the clearest picture to date of neuron death in Parkinson's disease, researchers at Columbia University Medical Center have found that a trio of culprits acting in concert is responsible for killing the brain cells.
A research team from the University of California, San Diego School of Medicine and the Salk Institute for Biological Studies in La Jolla has identified a protein in the brain of mice that protects neurons from excessive inflammation, which can lead to neurodegenerative disorders such as Parkinson's disease.
Teams of scientists from Australia and the United States have used yeast and mammalian cells to discover a connection between genetic and environmental causes of Parkinson's disease.
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