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Latest Alphavirus Stories

2014-07-07 12:24:18

LONDON, July 7, 2014 /PRNewswire/ -- Reportbuyer.com has added a new market research report: MarketVIEW: Ross River Virus vaccineshttp://www.reportbuyer.com/pharma_healthcare/therapeutic/marketview_ross_river_virus_vaccines.html Ross River Virus (RRV) is a mosquito-borne alphavirus (Togaviridae) mainly indigenous to Australia and the Western Pacific region. Infection with the virus can cause joint pain (polyarthritis/arthralgia) in humans which is reported to persist from between 3...

RNA Study On Barley Virus Reveals Key Link To The Crusades
2014-02-07 06:43:35

redOrbit Staff & Wire Reports - Your Universe Online Researchers at the University of Warwick have sequenced an ancient RNA genome for the first time ever. The RNA belonged to a barley virus once thought to be just 150 years old, but has now been determined to date back at least 2,000 years, revealing how extreme farming during the time of the Crusades contributed to its spread. The researchers detected and sequenced the RNA genome of Barley Stripe Mosaic Virus (BSMV) in a...

2014-01-31 10:44:45

HIV infection has many unhealthy consequences on the body, but in particular it messes up the gut. The human intestine has the highest concentration of HIV target cells, the majority of which are destroyed within days of infection, and before CD4 T cell counts drop measurably in the blood. A study published on January 30th in PLOS Pathogens reports the first three-dimensional ultra-structural study of HIV infection in vivo. Not only does it reveal details on how the virus quickly infects...

2013-08-22 12:50:53

Outbreak in Panama brought Latin America's first human cases of eastern equine encephalitis In the summer of 2010, the eastern Panamanian province of Darien experienced a phenomenon that had never been seen before in Latin America: a human outbreak of eastern equine encephalitis. The mosquito-borne virus that causes the disease is found all over the Americas, and infects horses throughout its range. Human infections are diagnosed every year in North America and are taken quite...

2013-05-10 11:47:31

A large scale, five year study of mosquitoes from different ecological regions in Kenya, including savannah grassland, semi-arid Acacia thorn bushes, and mangrove swamps, found a reservoir of viruses carried by mosquitoes (arboviruses) that are responsible for human and animal diseases. This research, published in BioMed Central's open access journal Virology Journal, highlights the need for continued surveillance in order to monitor the risk of disease outbreaks. Over 450,000 mosquitoes...

2010-12-01 22:52:22

Researchers have learned the atomic-scale arrangement of proteins in a structure that enables a virus to invade and fuse with host cells, showing precisely how the structure morphs with changing acidity to initiate infection. Findings from a team at Purdue University showed the protein structure in an acidic environment, and another team from the Pasteur Institute showed the same structure in a neutral environment. When combined, the two studies illustrate what happens to the structure as a...

2010-08-16 15:33:33

In a discovery that has implications for developing treatments against cancer and potentially deadly viruses, researchers at SUNY Downstate Medical Center have discovered the function of proteins that can enhance the progression of certain viruses and cancer cells. Their findings were published in the journal Genes and Development. According to Tatyana Pestova, PhD, DSc, assistant professor of cell biology, and Christopher Hellen, DPhil, associate professor of cell biology, "The significance...

2010-08-02 20:55:06

There are several challenges to be overcome if therapeutic anticancer vaccines, which are designed to boost the patient's anticancer immune response, are to be successfully developed. For example, the viruses used to deliver the tumor protein to the patient's immune system are themselves targeted by the patient's immune system, inducing neutralizing and suppressive responses. But now, a team of researchers, led by Michael Morse, at Duke University Medical Center, Durham, has developed a way...

2010-08-02 20:47:31

An experimental vaccine based on a virus that causes encephalitis in the wild appears to block tumor growth in some cases of advanced cancer, according to researchers at Duke University Medical Center. Scientists say the vaccine is able to stimulate an immune response, even in the face of profound immune system suppression, a condition most patients with advanced cancer experience. Scientists removed the genes that enable the Venezuelan equine encephalitis virus - an alphavirus - to replicate...

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2010-03-05 08:03:14

Mosquito-borne virus has infected millions of people in Asia, Africa and Europe Imagine a mosquito-borne virus that has already infected millions of people in recent outbreaks in South and Southeast Asia, the islands of the Indian Ocean, Africa and northern Italy. Although seldom fatal, it causes highly painful arthritis-like symptoms that can linger for months or even years. It's capable of adapting to spread through a mosquito species common in much of North America. And no vaccine or...


Latest Alphavirus Reference Libraries

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2011-02-23 20:55:25

The Semliki Forest virus was isolated from mosquitoes in the Semliki Forest in 1942. It can cause disease in both animals and man. It's an Alphavirus found in central, eastern, and southern Africa. It is a positive-stranded RNA virus. It is spread mainly by mosquito bites and infects mammals through inhalation or gastrointestinal exposure. The virus can cause lethal encephalitis in rodents; however, only one fatal infection has been reported in humans. This patient was immunodeficient and...

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2011-01-11 12:50:11

Eastern equine encephalitis virus (EEE), also called sleeping sickness or Triple E, is a zoonotic alphavirus and arbovirus that exists in the Americas and the Caribbean. It was first seen in Massachusetts in 1831 when 75 horses died of encephalitic illness. It is often associated with coastal plains. EEE was first isolated from the brain of an infected horse in 1933. In 1938 the first human case was confirmed when thirty children died of encephalitis in northeaster United States...

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Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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