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Last updated on April 19, 2014 at 18:42 EDT

Latest ALS Stories

2013-04-01 11:21:28

Role of cells other than motor neurons much larger than anticipated Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis (ALS), a fatal degenerative disease. The discovery holds promise, they say, for identifying new targets for interrupting the disease's progress. In a study described online in Nature Neuroscience, the...

2013-03-29 12:21:19

WASHINGTON, March 29, 2013 /PRNewswire-USNewswire/ -- The injection of antisense molecules into the space around the spinal cord of people with ALS is safe according to research published today. The first-in-human trial of this new therapy was funded by The ALS Association. The study was published today in the scientific journal Lancet Neurology. ALS, also known as Lou Gehrig's Disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. The...

2013-03-25 08:28:07

ROCKVILLE, Md., March 25, 2013 /PRNewswire/ -- Neuralstem, Inc. (NYSE MKT: CUR) announced today that it secured $8 million in debt financing with Hercules Technology Growth Capital (NYSE: HTGC), to fund the company's capital budget through late 2014. (Logo: http://photos.prnewswire.com/prnh/20061221/DCTH007LOGO) "This debt financing extends our cash runway well into late 2014 at a critical time in our clinical product development cycle. We have multiple NSI-566 cell therapy...

2013-03-15 08:29:56

NORDBORG, Denmark, March 15, 2013 /PRNewswire/ -- Danfoss A/S announced today that its wholly owned subsidiary, Danfoss Acquisition, Inc., has commenced its previously announced tender offer for all the shares of Sauer-Danfoss Inc. (NYSE: SHS) not already owned by Danfoss for $58.50 per share in cash. Sauer-Danfoss stockholders of record as of March 15, 2013 will also receive a cash dividend of $0.35 per share payable on March 29, 2013. Danfoss currently owns approximately 75.6% of the...

2013-03-14 16:27:35

WASHINGTON, March 14, 2013 /PRNewswire-USNewswire/ -- In research supported by The ALS Association and published in the online journal Neuron, scientists in London have shown that mutation in a gene that causes amyotrophic lateral sclerosis (ALS) reduces the energy supply in neurons and other cells--suggesting that the inability to produce sufficient quantities of energy is an important step in causing some cases of ALS. ALS, also known as Lou Gehrig's Disease, is a progressive...

2013-03-13 08:34:40

James Berry, M.D., M.P.H., 2013 Recipient WASHINGTON, March 13, 2013 /PRNewswire-USNewswire/ -- The ALS Association and the American Academy of Neurology (AAN) are pleased to announce that James Berry, M.D., M.P.H., from the Department of Neurology, Massachusetts General Hospital, Boston, Mass., is this year's recipient for the Richard Olney AAN/ALS Association Clinician Scientist Development Award, which is a part of The Association's research program TREAT ALS (Translational Research...

2013-03-12 12:27:58

Rosa Rademakers, Ph.D. and Bryan Traynor, M.D., Ph.D. Receive Essey Award WASHINGTON, March 12, 2013 /PRNewswire-USNewswire/ -- On Tuesday, March 19, The ALS Association and the American Academy of Neurology (AAN) will present the 2013 Sheila Essey Award for ALS Research at AAN's annual meeting in San Diego, California to Rosa Rademakers, Ph.D. and Bryan Traynor, M.D. Ph.D. These two scientists independently identified a mutation in the C9orf72 gene, on Chromosome 9, that causes ALS, a...

2013-03-04 23:05:52

St. Jude Children's Research Hospital ties mutations in 2 genes to the death of motor neurons associated with ALS, or Lou Gehrig's disease, and other devastating neurodegenerative problems A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases. The same mutation occurred in both genes and led to the...

2013-03-04 13:20:32

Proteins with mutations in 'prion-like' segments considered candidates for inherited forms of ALS, multisystem proteinopathy A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders. James Shorter, Ph.D., assistant professor of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania, Paul Taylor, M.D., PhD, St. Jude Children's Research Hospital, and colleagues describe in an advanced online...

2013-03-04 11:15:32

Shortage of protein TDP-43 causes muscle wasting and stunted nerve cells A shortage of a protein called TDP-43 caused muscle wasting and stunted nerve cells. This finding supports the idea that malfunction of this protein plays a decisive role in ALS and FTD. The study is published in the "Proceedings of the National Academy of Sciences of the USA" (PNAS). ALS is an incurable neurological disease which manifests as rapidly progressing muscle wasting. Both limbs and respiratory muscles...