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Latest American Association for Cancer Research Stories

2012-02-03 19:00:39

Soy isoflavone supplements did not decrease breast cancer cell proliferation in a randomized clinical trial, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Lead researcher Seema A. Khan, M.D., professor of surgery at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, said the results of this study are consistent with the findings of previous studies that were designed to test cancer...

2012-02-03 14:00:00

Stand Up To Cancer & Union for International Cancer Control collaborate to urge participants from around the world to pledge better health choices at http://WorldCancerDay.SU2C.org Geneva, Switzerland / New York (PRWEB) February 03, 2012 Stand Up To Cancer (SU2C) and the Union for International Cancer Control (UICC) announced a long-term alliance today, with a multi-platform collaborative campaign in support of World Cancer Day on Saturday, February 4, 2012. Issuing a global call to...

2012-01-18 15:03:36

Most research on glioblastoma development, a complicated tumor of the brain with a poor prognosis, has focused on the gene transcription level, but scientists suggest that post-transcriptional regulation could be equally or even more important. In a recent report in Molecular Cancer Research, a journal of the American Association for Cancer Research, scientists led by Luiz O. F. Penalva, Ph.D., an assistant professor in the department of cellular and structural biology at the University of...

2012-01-11 10:09:11

Smoking may be associated with the development of molecular features of cancer in the large airway epithelium. In the small airway epithelium, molecular cancerization is associated with development of chronic obstructive pulmonary disease, according to recent data. "We are striving to find the earliest molecular changes that are induced by environmental stressors – in this case, smoking," said Renat Shaykhiev, M.D., Ph.D., assistant professor of genetic medicine at Weill Cornell...

2012-01-11 10:08:01

The investigational drug ganetespib, a synthetic second-generation Hsp90 inhibitor, slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. The drug was even more active when combined with traditional lung cancer treatments and other investigational targeted therapies, according to preclinical study data. David A. Proia, Ph.D., and Jaime Acquaviva, Ph.D., scientists at Synta Pharmaceuticals Corp., presented the data at the AACR-IASLC...

2012-01-10 11:32:25

Sorafenib was effective in patients with non-small cell lung cancer and a KRAS mutation, but survival rates were reportedly "unsatisfactory," according to data presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Biology, Therapy and Personalized Medicine, held Jan. 8-11, 2012. Patients with lung cancer and a KRAS mutation are believed to have a poor prognosis and may not benefit from treatment with epidermal growth factor receptor tyrosine kinase inhibitors,...

2012-01-09 19:52:47

Researchers have begun to identify which mutations and pathway changes lead to lung cancer in never-smokers – a first step in developing potential therapeutic targets. Never-smokers (defined as an individual who smoked fewer than 100 cigarettes in his or her lifetime) are estimated to account for 10 percent of lung cancer cases. However, in the past, researchers have not examined this patient population as extensively as they have studied patients with lung cancer who smoked,...

2012-01-09 19:51:39

Multicentric carcinogenesis with the same genetic mutation appears to occur in lung adenocarcinoma, according to data presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Biology, Therapy and Personalized Medicine, held Jan. 8-11, 2012. Data also demonstrated that the EGFR and KRAS genes, which are mutually exclusive, can be used to define clinically relevant molecular subsets of lung adenocarcinoma and can define tumor clonality. "The information on genetic...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.