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Latest American Thoracic Society Stories

2012-01-06 12:03:02

A large percentage of patients with mild-to-moderate asthma have persistently non-eosinophilic disease which may not respond to currently available anti-inflammatory treatments, according to a new study. In a cross-sectional study of 995 asthmatic subjects enrolled in nine clinical trials conducted by the NHLBI's Asthma Clinical Research Network, sputum eosinophilia (2% eosinophils) was found in only 36% of asthmatics not using an inhaled corticosteroid (ICS) and 17% of those using an ICS....

2012-01-03 22:04:26

To reduce mortality and improve patient care in the nation's ICUs, a task force formed by the Critical Care Societies Collaborative (CCSC), in conjunction with the US Critical Illness and Injury Trials Group (USCIITG) has recommended that research in the field become less fragmented and better account for patient heterogeneity and the complexity of critical illness. The CCSC comprises the American Thoracic Society (ATS), the American Association of Critical-Care Nurses (AACN), the American...

2011-12-16 12:58:51

Inhaled glucocorticoids for the treatment of asthma during pregnancy are not associated with an increased risk of most diseases in offspring, but may be a risk factor for endocrine and metabolic disturbances, according to a new study. In a population-based cohort study, 65,085 mother-child pairs from the Danish National Birth Cohort were followed up in real time from early pregnancy into childhood. "Maternal use of inhaled glucocorticoids for asthma during pregnancy was not related to an...

2011-12-10 01:17:10

In populations with a low prevalence of tuberculosis (TB), the majority of positives with the three tests commercially available in the U.S for the diagnosis of TB are false positives, according to a new study. "We compared commercially available tests for latent tuberculosis infection (LTBI) in a diverse population with a low LTBI prevalence," said James Mancuso, MD, DrPH, of the Walter Reed Army Institute of Research Preventive Medicine Residency Program. "Our results suggest that in...

2011-12-10 01:15:55

The incidence of tuberculosis (TB) diagnosis is significantly increased in mothers postpartum, suggesting a potential new population to target for screening, according to a new UK-wide cohort study. In the joint study between the Health Protection Agency and the University of East Anglia, researchers analyzed data on all women with pregnancies between 1996 and 2008 from the General Practice Research Database, which contains records from 460 practices across the UK, representing 5.5 percent...

2011-12-10 01:14:41

Depressive symptoms and impaired physical function were common and long-lasting during the first two years following acute lung injury (ALI), according to a new study from Johns Hopkins University School of Medicine. Depressive symptoms were an independent risk factor for impaired physical function. "Early identification and treatment of depressive states should be evaluated as a potential intervention to improve long-term outcomes in ALI survivors," said first author O. Joseph Bienvenu,...

2011-11-18 07:10:41

Metabolic syndrome biomarkers predict subsequent decline in lung function after particulate exposure, according to new research involving rescue personnel exposed to World Trade Center (WTC) dust. In a nested case-control study of 327 non-smoking FDNY 9/11 rescue workers, metabolic syndrome biomarkers measured within six months of exposure to WTC dust predicted decline of forced expiratory volume in one second (FEV1) over the next six years. "Study participants with dyslipidemia,...

2011-10-21 10:25:48

Although increased use of noninvasive positive-pressure ventilation (NIPPV) nationwide has helped decrease mortality rates among patients hospitalized with chronic obstructive pulmonary disease (COPD), a small group of patients requiring subsequent treatment with invasive mechanical ventilation (IMV) have a significantly higher risk of death than those placed directly on IMV, according to researchers in the United States who studied patterns of NIPPV use. The findings were published online...

2011-09-23 11:39:28

Treatment with the calcium-sensitizing drug levosimendan may be effective in improving muscle function in patients with respiratory muscle weakness, which often accompanies chronic diseases such as chronic obstructive pulmonary disease (COPD) and congestive heart failure, according to researchers in the Netherlands, who studied the effects of the drug on healthy volunteers. The drug, which is normally prescribed in patients with acute heart failure, increases the sensitivity of muscle tissue...

2011-09-22 21:36:38

Children with severe therapy-resistant asthma (STRA) may have poorer lung function and worse symptoms compared to children with moderate asthma, due to lower levels of vitamin D in their blood, according to researchers in London. Lower levels of vitamin D may cause structural changes in the airway muscles of children with STRA, making breathing more difficult. The study provides important new evidence for possible treatments for the condition. The findings were published online ahead of...


Word of the Day
caparison
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.
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