Latest AMPA receptor Stories
There are new clues about malfunctions in brain cells that contribute to intellectual disability and possibly other developmental brain disorders.
About half of newborns who have seizures go on to have long-term intellectual and memory deficits and cognitive disorders such as autism, but why this occurs has been unknown.
Scientists at Cold Spring Harbor Laboratory (CSHL) have solved part of a puzzle concerning the relationship between changes in the strength of synapses – the tiny gaps across which nerve cells in the brain communicate – and dysfunctions in neural circuits that have been linked with drug addiction, mental retardation and other cognitive disorders.
A tiny piece of a critical receptor that fuels the brain and without which sentient beings cannot live has been discovered by University at Buffalo scientists as a promising new drug target for Alzheimer's and other neurodegenerative diseases.
Researchers working with adult mice have discovered that learning and memory were profoundly affected when they altered the amounts of a certain protein in specific parts of the mammals' brains.
By creating a better way to see molecules at work in living brain cells, researchers affiliated with MIT's Picower Institute for Learning and Memory and the MIT Department of Chemistry are helping elucidate molecular mechanisms of synapse formation.
Researchers at the University of Illinois have identified a potential drug target for the treatment of Alzheimerâ€™s disease: a receptor that is embedded in the membrane of neurons and other cells.
Johnâ€™s Hopkins researchers have shown that interactions between the PICK1 protein and another group of proteins known as AMPA receptors are important for allowing certain nerve cells to learn.
- To writhe; struggle or twist about with more or less force; wriggle.
- To scribble, jot.