Quantcast

Latest Amylin Stories

2014-07-11 13:26:52

IOS Press Monitoring formation of amylin plaques using 2-D IR spectroscopy, scientists have observed the creation of temporary intermediate structures, which may explain why proteins aggregate into toxic plaques Amyloid diseases, such as Alzheimer's disease, type 2 diabetes, cataracts, and the spongiform encephalopathies, all share the common trait that proteins aggregate into long fibers which then form plaques. Yet in vitro studies have found that neither the amylin monomer...

Newly Discovered Compound Slows Natural Degradation Of Insulin In The Body
2014-05-22 03:32:32

By Peter Reuell, Harvard University With the discovery of a compound that can slow the degradation of insulin in animals, scientists at Harvard have opened the door to a potential new treatment for diabetes. The new approach, described by David Liu, professor of chemistry and chemical biology, and Alan Saghatelian, associate professor of chemistry and chemical biology, uses the compound to inhibit insulin-degrading enzyme (IDE). Inhibiting IDE in mice, they have shown, elevates insulin...

2013-11-12 12:08:40

People get type 2 diabetes. So do cats. But rats don't, and neither do dogs. Subtle differences in the shape of proteins protect some and endanger others. "All mammals make this same protein called amylin, and it only differs a little bit from species to species," says Martin Zanni, a University of Wisconsin–Madison chemistry professor. "The mammals that get type 2 diabetes, their amylin proteins aggregate in the pancreas into plaque that kills the cells around them. As a result, you...


Word of the Day
blee
  • Color; hue; complexion.
This word is Middle English in origin.
Related