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Latest Amyloid precursor protein secretase Stories

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2012-07-13 07:06:17

Connie K. Ho for redOrbit.com - Your Universe Online 5 million. That´s the number of people in the U.S. suffering from Alzheimer´s disease, according to a recent CNN article. Scientists recently announced that they had discovered a gene that fights Alzheimer´s. This is a positive step forward as the gene could help develop treatments to fight the disorder. In the journal Nature, researchers explained how the gene that caused an early form of Alzheimer´s could also be...

2012-03-08 01:03:09

Researchers at the University of California, San Diego, the Medical University of South Carolina, the University of Cincinnati, and American Life Science Pharmaceuticals of San Diego have validated the protease cathepsin B (CatB) as a target for improving memory deficits and reducing the pathology of Alzheimer's disease (AD) in an animal model representative of most AD patients. The study has been published in the online edition of the Journal of Alzheimer's Disease. According to...

2011-11-21 22:54:41

Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology (www.jcb.org). Abeta, the toxic protein that accumulates in the brains of Alzheimer's patients, is formed when enzymes cut up its parental protein, known as amyloid precursor protein. One of those enzymes is beta-secretase or BACE1. BACE1 cycles between the Golgi apparatus and the plasma membrane, traveling through endosomes...

2011-08-07 00:00:04

Nutri-Med Logic Corp discusses the role of R-Alpha Lipoic and Omega-3 as a vehicle to improve the homeostasis. It has been suggested that redox imbalance causes alteration in the production of the protein Amyloid Beta pathways (gamma vs. alpha secretase) and that could be translated to the wrong vs. right amyloid protein synthesis in cases of Alzheimer / cognitive decline (PRWEB) August 06, 2011 Nutri-Med Logic Corp: Benefits of proper nutrition such as R-Alpha Lipoic and Omega-3 in...

2011-07-18 05:30:00

CAMBRIDGE, Mass., July 18, 2011 /PRNewswire/ -- Satori(TM) Pharmaceuticals today announced the presentation of two posters at the Alzheimer's Association International Conference on Alzheimer's Disease (ICAD) taking place in Paris, France, July 16-21, 2011. Both posters illuminate the unique biological activity associated with Satori's approach to the treatment of Alzheimer's disease. The posters were titled, "Gamma-secretase modulators do not show a potency shift in high expressing model...

2011-05-31 12:36:52

Researchers pinpoint a small RNA that spurs cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease (AD) or other types of neurodegeneration. The study appears in the May 30 issue of The Journal of Cell Biology (www.jcb.org). Like a movie with an alternate ending, a protein can come in more than one version. Although scientists have identified numerous proteins and RNAs that influence alternative splicing, they haven't deciphered...

2011-05-31 06:47:52

(Ivanhoe Newswire) "“ Researchers pinpoint a small RNA that triggers cells to manufacture a particular splice variant of a key neuronal protein, potentially promoting Alzheimer's disease (AD) or other types of neurodegeneration. Like a movie with an alternate ending, a protein can come in more than one version. Although scientists have identified numerous proteins and RNAs that influence alternative splicing, they haven't deciphered how cells fine-tune the process to produce specific...

2011-03-25 18:34:03

A drug used to treat asthma has been shown to help reduce the formation of amyloid beta, a peptide in the brain that is implicated in the development of Alzheimer's disease, according to researchers at Temple University's School of Medicine. The researchers published their findings, "Pharmacologic Blockade of 5-Lipoxygenase Improves the Amyloidotic Phenotype of an AD Transgenic Mouse Model," in the American Journal of Pathology. In previous studies, the Temple researchers discovered that...

2010-10-12 18:38:00

Mount Sinai School of Medicine researchers have found that a gene associated with the onset of Type 2 diabetes also is found at lower-than-normal levels in people with Alzheimer's disease. The research, led by Giulio Maria Pasinetti, MD, PhD, The Saunder Family Professor in Neurology, and Professor of Psychiatry and Geriatrics and Adult Development at Mount Sinai School of Medicine, was published this month in Aging Cell. The new study provides insight into a potential mechanism that might...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.