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Latest Amyloid precursor protein Stories

2014-08-18 08:29:41

Neurotrope's Collaborator BRNI, Publishes Article in the Journal of Alzheimer's Disease describing correlation of PKCe levels and degree of disease PLANTATION, Fla., Aug. 18, 2014 /PRNewswire/ -- Neurotrope, Inc. (OTCQB: NTRP) today announced that results from a new study, entitled, "PKCe Deficits in Alzheimer's Disease Brains and Skin Fibroblasts," published in the recent edition of the peer-reviewed Journal of Alzheimer's Disease and co-authored by Tapan K. Khan, Ph.D.; Abhik Sen,...

2014-07-16 04:21:24

- New Brain Protein Connected for First Time to Cognitive Decline and Alzheimer's Disease. COPENHAGEN, Denmark, July 16, 2014 /PRNewswire-USNewswire/ -- Results from four research studies reported as "developing topics" at the Alzheimer's Association International Conference(®) 2014 (AAIC(®) 2014) in Copenhagen include significant advances in evidence regarding treatment and early detection of Alzheimer's disease and dementia, as well as new ideas in the basic brain science of dementia that...

2014-07-14 12:20:58

Cedars-Sinai Medical Center Preliminary results show the device, created at Cedars-Sinai and developed by NeuroVision Imaging, may provide highly predictive early detection of changes associated with Alzheimer's disease A noninvasive optical imaging device developed at Cedars-Sinai can provide early detection of changes that later occur in the brain and are a classic sign of Alzheimer's disease, according to preliminary results from investigators conducting a clinical trial in...

2014-07-13 12:20:48

Study Results Presented at the Alzheimer's Association International Conference 2014 INDIANAPOLIS, July 13, 2014 /PRNewswire/ -- Eli Lilly and Company (NYSE: LLY) today announced results from its non-clinical study in genetically engineered mice examining combination therapy with the murine version of the beta-amyloid antibody N3pG and beta-secretase inhibitor BACE (LY2811376). Data results found that combination therapy was more effective in removing clumps of amyloid-beta protein...

2014-07-13 04:20:20

New Alzheimer's biomarker results reported at Alzheimer's Association International Conference 2014 COPENHAGEN, Denmark, July 13, 2014 /PRNewswire-USNewswire/ -- A decreased ability to identify odors might indicate the development of cognitive impairment and Alzheimer's disease, while examinations of the eye could indicate the build-up of beta-amyloid, a protein associated with Alzheimer's, in the brain, according to the results of four research trials reported today at the...

Specific Mechanisms Of Alzheimer’s Disease Countered By Cocoa Extract
2014-06-24 03:38:45

Mount Sinai Hospital Insights into mechanisms behind cocoa’s benefit may lead to new treatments or dietary regimens A specific preparation of cocoa-extract called Lavado may reduce damage to nerve pathways seen in Alzheimer’s disease patients’ brains long before they develop symptoms, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published June 20 in the Journal of Alzheimer’s Disease (JAD). Specifically, the study results, using mice...

2014-05-21 11:48:44

Saint Louis University A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease. The molecule also reduced inflammation in the part of the brain responsible for learning and memory. The paper, authored by a team of scientists led by Susan Farr, Ph.D., research professor of geriatrics at Saint Louis University,...

2014-04-21 13:49:52

Compounds identified that stabilize retromer protein complex, which protects neurons from amyloid-beta A team of researchers from Columbia University Medical Center (CUMC), Weill Cornell Medical College, and Brandeis University has devised a wholly new approach to the treatment of Alzheimer's disease involving the so-called retromer protein complex. Retromer plays a vital role in neurons, steering amyloid precursor protein (APP) away from a region of the cell where APP is cleaved, creating...

2014-04-16 11:43:12

UC Irvine neurobiologists have found that genetically modified neural stem cells show positive results when transplanted into the brains of mice with the symptoms and pathology of Alzheimer's disease. The pre-clinical trial is published in the journal Stem Cells Research and Therapy, and the approach has been shown to work in two different mouse models. Alzheimer's disease, one of the most common forms of dementia, is associated with accumulation of the protein amyloid-beta in the brain in...

2014-04-14 14:20:45

Alzheimer's disease, the primary cause of dementia in the elderly, imposes a tremendous social and economic burden on modern society. In Japan, the burden of the disease in 2050 is estimated to be a half a trillion US dollars, a figure equivalent to the government's annual revenues. Unfortunately, it has proven very difficult to develop drugs capable of ameliorating the disease. After a tremendous burst of progress in the 1990s, the pace of discoveries has slowed. Dr. Saido believes that...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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