Latest Amyloid precursor protein Stories

Brain Boosting Activities Early In Life May Cut Later Risk Of Alzheimer’s
2012-01-25 06:32:24

A new study suggests that people who engage in mentally stimulating activities such as reading and playing games — particularly early in life -- may be lowering levels of a brain protein linked to Alzheimer's disease. The protein, known as beta-amyloid protein, is the main component of the destructive brain-clogging plaques that are a hallmark of Alzheimer´s disease. Researchers at the University of California Berkeley surveyed 65 healthy elderly people, whose average age was...

2012-01-10 11:44:40

Discovery may lead to better understanding of the disease, possible therapies With a lack of effective treatments for Alzheimer's, most of us would think long and hard about whether we wanted to know years in advance if we were genetically predisposed to develop the disease. For researchers, however, such knowledge is a window into Alzheimer's disease's evolution. Understanding the biological changes that occur during the clinically "silent" stage – the years before symptoms...

Alzheimer's Drug Candidate Could Prevent Disease Progression
2011-12-15 04:55:47

[ Watch the Video ] Salk scientists develop new drug that improves memory and prevents brain damage in mice A new drug candidate may be the first capable of halting the devastating mental decline of Alzheimer's disease, based on the findings of a study published Dec. 14 in PLoS ONE. When given to mice with Alzheimer's, the drug, known as J147, improved memory and prevented brain damage caused by the disease. The new compound, developed by scientists at the Salk Institute for...

2011-12-01 01:20:45

One of the earliest known impairments caused by Alzheimer's disease - loss of sense of smell — can be restored by removing a plaque-forming protein in a mouse model of the disease, a study led by a Case Western Reserve University School of Medicine researcher finds. The study confirms that the protein, called amyloid beta, causes the loss. "The evidence indicates we can use the sense of smell to determine if someone may get Alzheimer's disease, and use changes in sense of smell to...

2011-11-21 22:54:41

Sluggish recycling of a protein-slicing enzyme could promote Alzheimer's disease, according to a study published online on November 21 in The Journal of Cell Biology (www.jcb.org). Abeta, the toxic protein that accumulates in the brains of Alzheimer's patients, is formed when enzymes cut up its parental protein, known as amyloid precursor protein. One of those enzymes is beta-secretase or BACE1. BACE1 cycles between the Golgi apparatus and the plasma membrane, traveling through endosomes...

2011-10-27 22:07:46

In a development that sheds new light on the pathology of Alzheimer's disease (AD), a team of Whitehead Institute scientists has identified connections between genetic risk factors for the disease and the effects of a peptide toxic to nerve cells in the brains of AD patients. The scientists, working in and in collaboration with the lab of Whitehead Member Susan Lindquist, established these previously unknown links in an unexpected way. They used a very simple cell type–yeast...

2011-10-15 07:00:00

Ever looked out the windshield on the way to work wondering, âœWhere the heck did THOSE storm clouds from?â Donât be the last guy on your block still doing that. FireWhat Inc. has your weather woes covered. Dunsmuir, CA (PRWEB) October 15, 2011 21st century satellite imagery and constantly updated local weather in one place? How come no one has done this before?! FireWhat Inc., a Dunsmuir, CA start-up, has created the definitive weather...

2011-09-28 09:21:34

Animal study may suggest way to rescue cells from disease A protein linked to Alzheimer's disease kills nerve cells that detect odors, according to an animal study in the September 28 issue of The Journal of Neuroscience. The findings shed light on why people with Alzheimer's disease often lose their sense of smell early on in the course of the disease. "Deficits in odor detection and discrimination are among the earliest symptoms of Alzheimer's disease, suggesting that the sense of...

Award-winning Research Points Toward Alzheimer’s Vaccine
2011-09-27 03:44:50

An accomplice to the protein that causes plaque buildup in Alzheimer's disease is the focus of a potential new treatment, according to research by a Georgia Health Sciences University graduate student. In Alzheimer's, the amyloid protein can accumulate in the brain instead of being eliminated by the body's natural defenses, nestling between the neurons and forming impassable plaques. Amyloid and the way it gets there could be targets for a new vaccine. "RAGE, or receptor for advanced...

Word of the Day
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.