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Latest Amyloid precursor protein Stories

2011-09-01 16:37:55

Alzheimer disease (AD) is the most common cause of dementia among older people. One of the main features of AD is the presence in the brain of abnormal clumps of the protein fragment beta-amyloid, which are known as amyloid plaques. A team of researchers, led by Jens Pahnke, at the University of Rostock, Germany, has now identified a way to reduce the amount of beta-amyloid in the brains of mice with a disease that models AD, providing hope that a similar approach might be possible in...

2011-09-01 15:24:41

Researchers have found that a protein variation linked by some genetic studies to Alzheimer's disease is consistently present in the brains of people with Alzheimer's. In further biochemical and cell culture investigations, they have shown that this protein, known as ubiquilin-1, performs a critical Alzheimer's-related function: it "chaperones" the formation of amyloid precursor protein, a molecule whose malformation has been directly tied to Alzheimer's pathology. "What we saw here is...

2011-08-18 00:00:41

A new iPhone App called It's Done! is helping brain injury survivors remember whether they turned off the stove, locked the door, or took their medication. For those dealing with short term memory problems, the app instantly confirms the completion of everyday routine tasks. Houston, TX (PRWEB) August 17, 2011 A new iPhone App called It's Done! is helping brain injury survivors remember whether they turned off the stove, locked the door, or took their medication. For those dealing with...

2011-08-15 22:31:35

A modified form of the enzyme Cdk5 is elevated in the brains of Alzheimer's disease patients, where it triggers damage to nerve cell connections Alzheimer's disease is characterized by abnormal proteins that stick together in little globs, disrupting cognitive function (thinking, learning, and memory). These sticky proteins are mostly made up of beta-amyloid peptide. A better understanding of these proteins, how they form, and how they affect brain function will no doubt improve the diagnosis...

2011-08-11 08:00:00

NEW YORK, Aug. 11, 2011 /PRNewswire/ -- Citeline, an Informa business unit, and the world's leading research authority on pharmaceutical clinical trials recently reviewed the findings from the 14th International Conference on Alzheimer's Disease (ICAD 2011/AAIC 2011) July 16-21, 2011, noting that while pharma continues to develop beta amyloid targeting drugs, amyloid targets are moving ahead in terms of biomarkers and early warning for risk of Alzheimer's. According to Dr. Revati Tatake,...

2011-07-30 00:01:04

Market-Leading iPad App Developer missingSTEP Partners with Recognia for New App Specifically for the iPad with New Features and Unique Pattern Recognition San Francisco, Ca (PRWEB) July 29, 2011 missingSTEP today announced the launch of a new iPad app, "Stock Chart Patterns", one of the only apps to use Apple Inc.'s subscription offering as a standalone service. The app was built in partnership with Recognia and will provide users an intuitive investment research tool by automatically...

2011-07-20 03:30:00

- New Reports Highlight Advances in Early Detection and Global Collaborations - - French President Sarkozy Addresses Researchers on National Alzheimer's Plan - PARIS, July 20, 2011 /PRNewswire-USNewswire/ -- This week, more than 5,000 scientists from around the world gathered in Paris to report the latest advances in Alzheimer's research at the Alzheimer's Association® International Conference 2011 (AAIC 2011). Scientists presented and discussed early detection, medical...

2011-07-19 03:00:00

INDIANAPOLIS, July 19, 2011 /PRNewswire/ -- Data were presented today from the first of two Phase III trials of semagacestat, including data from a 32 week follow-up period after dosing was halted in August 2010. Semagacestat is a gamma secretase inhibitor that had been studied as a potential treatment for Alzheimer's disease. Results shown today provided patient outcomes from the active treatment portion of the study and from a modified portion of the study conducted after dosing with...

2011-07-18 15:11:36

Researchers at Mount Sinai School of Medicine have identified how a gene for a protein that can cause Type 2 diabetes, also possibly kills nerve cells in the brain, thereby contributing to Alzheimer's disease. The gene, called SorCS1, controls the generation of amyloid-beta (Abeta) in the brain. Abeta plays a key role in the development of Alzheimer's disease. The researchers previously linked SorCS1 to Alzheimer's disease and identified where the molecules lived in the cell, but not how they...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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