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Latest Amyloid precursor protein Stories

2011-07-19 03:00:00

INDIANAPOLIS, July 19, 2011 /PRNewswire/ -- Data were presented today from the first of two Phase III trials of semagacestat, including data from a 32 week follow-up period after dosing was halted in August 2010. Semagacestat is a gamma secretase inhibitor that had been studied as a potential treatment for Alzheimer's disease. Results shown today provided patient outcomes from the active treatment portion of the study and from a modified portion of the study conducted after dosing with...

2011-07-18 15:11:36

Researchers at Mount Sinai School of Medicine have identified how a gene for a protein that can cause Type 2 diabetes, also possibly kills nerve cells in the brain, thereby contributing to Alzheimer's disease. The gene, called SorCS1, controls the generation of amyloid-beta (Abeta) in the brain. Abeta plays a key role in the development of Alzheimer's disease. The researchers previously linked SorCS1 to Alzheimer's disease and identified where the molecules lived in the cell, but not how they...

2011-07-18 05:30:00

CAMBRIDGE, Mass., July 18, 2011 /PRNewswire/ -- Satori(TM) Pharmaceuticals today announced the presentation of two posters at the Alzheimer's Association International Conference on Alzheimer's Disease (ICAD) taking place in Paris, France, July 16-21, 2011. Both posters illuminate the unique biological activity associated with Satori's approach to the treatment of Alzheimer's disease. The posters were titled, "Gamma-secretase modulators do not show a potency shift in high expressing model...

2011-07-17 05:30:00

PARIS, July 17, 2011 /PRNewswire-USNewswire/ -- As the Alzheimer's field moves closer to new and earlier tests for the disease, innovative global research initiatives are taking the first important steps to standardize Alzheimer's biomarkers, as evidenced by two presentations made today at the Alzheimer's Association(R) International Conference 2011 (AAIC 2011) in Paris. One study compared, for the first time, results of brain amyloid imaging and the impact of genetics and ethnicity...

2011-07-09 00:00:30

Nonprofit AHAF announces $5.6 million in grants for Alzheimer's and eye disease research to scientists worldwide. Includes $3.4 million for Alzheimer's disease. Clarksburg, MD (PRWEB) July 08, 2011 Alzheimer's disease scientists: >    Examine the Role of Sleep in Memory Loss; >    Assess Genetic Risks for the Disease; >    Move Closer to Human Clinical Trials on Drug Therapies The American Health Assistance Foundation...

2011-06-29 18:13:55

Overexpression of gene is linked with Alzheimer's disease and down syndrome Chronic stress has long been linked with neurodegeneration. Scientists at USC now think they may know why. The study, which has tremendous implications for understanding and treating Alzheimer's disease, was published in the June issue of The FASEB Journal (the Journal of the Federation of American Societies for Experimental Biology). Corresponding author Kelvin J. A. Davies, the James E. Birren Chair at the USC Davis...

2011-06-14 13:38:51

Researchers at North Carolina State University have figured out how copper induces misfolding in the protein associated with Parkinson's disease, leading to creation of the fibrillar plaques which characterize the disease. This finding has implications for both the study of Parkinson's progression, as well as for future treatments. The protein in question, alpha-synuclein, is the major component of fibrillar plaques found in Parkinson's patients. Researchers had already discovered that...

2011-05-31 21:15:59

Researchers at the University of California, San Diego, the Medical University of South Carolina and American Life Science Pharmaceuticals of San Diego have demonstrated that oral administration of a cysteine protease inhibitor, E64d, not only reduces the build-up of ÃŽ²-amyloid (AÃŽ²) in the brains of animal models for Alzheimer's disease, but also results in a substantial improvement in memory deficit. A paper detailing the findings has been published as an...

2011-05-18 00:01:31

In just one month iPodiatrist iPhone App has touched down in every corner of the world bringing the importance of foot health to every inhabited continent on the planet. Dr. Alec Hochstein the "iPodiatrist" has fielded questions from patients, students, and doctors on every one of them, from diabetic footcare to bunions and hammertoes. Great Neck, NY (PRWEB) May 17, 2011 iPodaitrist was uploaded to the Apple App store just three weeks ago and has been received with tremendous interest....

2011-05-13 11:03:48

What if you were told you carried a gene that increases your risk for Alzheimer's disease? And what if you were told this gene starts to do its damage not when you're old but when you're young? Brace yourself. Scientists know there is a strong genetic component to the development of late-onset Alzheimer's. In 1993, researchers discovered a gene known as ApoE4 "” carried by about a quarter of us "” that triples the risk for getting Alzheimer's. In 2009, three more risky genes were...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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