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Latest Amyloid precursor protein Stories

2010-09-09 01:09:20

Data published in Neuron demonstrate proof of concept in long term prevention of disease pathology in a mouse model, without GI side effects In the Sept 9, 2010 issue of Neuron, Neurogenetic Pharmaceuticals, Inc. (NGP) reports proof of concept studies that show its proprietary compound, NGP 555, is effective in preventing the amyloid pathology of Alzheimer's disease (AD) in a transgenic mouse model. The study further demonstrates that following chronic treatment with the gamma secretase...

2010-08-23 13:23:32

New study shows GM-CSF reduces AD pathology and eliminates memory loss A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer's disease pathology and reversed the memory impairment of mice bred to develop symptoms of the neurodegenerative disease, a new study by the University of South Florida reports. Researchers found that the protein, GM-CSF, likely stimulates the body's natural scavenger cells to attack and remove Alzheimer's amyloid deposits in the...

2010-08-17 07:00:00

INDIANAPOLIS, Aug. 17 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY) will halt development of semagacestat, a gamma secretase inhibitor being studied as a potential treatment for Alzheimer's disease, because preliminary results from two ongoing long-term Phase III studies showed it did not slow disease progression and was associated with worsening of clinical measures of cognition and the ability to perform activities of daily living. The company's decision does not affect...

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2010-08-10 20:30:19

UCI researchers locate brain passage that could aid early diagnosisWith the help of volunteers aged 18 to 89, UC Irvine researchers have identified for the first time in humans a long-hidden part of the brain called the perforant path. Scientists have struggled for decades to locate the tiny passage, which is believed to deteriorate gradually as part of normal aging and far more quickly due to Alzheimer's disease."The nice thing about this is we may be able to predict Alzheimer's very early,"...

2010-07-19 09:00:00

To view the Social Media Release, click here: http://smr.newswire.ca/en/goexplore-canada/canadas-biggest-travel-app-for-smartphones HALIFAX, July 19 /PRNewswire/ - The producers say goExplore Canada will show you where to go, what to see, where to stay, where to eat and just "where the heck am I?" It's just been released in the Apple app store and will be available in the Android Market around the end of the month. The free app uses detailed maps and includes more than 3,000 Points of...

2010-07-15 13:41:03

Finding points toward preventive strategy for diabetics, as well as value of predictive test for dementia in nondiabetics Researchers from Mayo Clinic's Florida campus say that dementia in some diabetics appears to be caused often by vascular disease in the brain, and the dementia that develops in people without diabetes is more likely associated with deposition of the plaque seen in people with Alzheimer's disease. The findings were presented at the Alzheimer's Association International...

2010-07-14 12:30:00

HONOLULU, July 14 /PRNewswire-USNewswire/ -- This week, nearly 4,000 scientists from around the world gathered to report and discuss the latest advances in research on treatments, risk factors, and diagnosis for the health epidemic of the 21st century - Alzheimer's disease - at the Alzheimer's Association's 2010 International Conference on Alzheimer's Disease (AAICAD 2010) in Honolulu. "With an aging baby boomer generation, the Alzheimer's disease crisis will continue to touch more lives...

2010-07-14 12:30:00

- - New Alzheimer's Risk Gene May Affect Memory Scores and Brain Atrophy in Middle Age - - Clinical Trial of Intranasal Insulin Shows Benefits in Alzheimer's and MCI - - Known Alzheimer's Risk Gene May Change Shape of Brain Deposits - HONOLULU, July 14 /PRNewswire-USNewswire/ -- Last minute scientific submissions to the Alzheimer's Association International Conference on Alzheimer's Disease 2010 (AAICAD 2010) in Honolulu, HI, known as "hot topics," suggest that (1) a newly-discovered...

2010-07-14 12:00:00

HONOLULU, July 14 /PRNewswire/ -- EnVivo Pharmaceuticals today announced at the Alzheimer's Association 2010 International Conference on Alzheimer's Disease (ICAD) results from its proprietary gamma-secretase modulator (GSM) pre-clinical study. In a transgenic mouse model, EnVivo's EVP-0015962 reduced amyloid plaque buildup which is believed to be a cause of Alzheimer's disease, reversed behavioral deficits and reduced brain inflammation associated with Alzheimer's disease. EVP-0015962...

2010-07-12 19:30:00

- When Combined with a Known Alzheimer's Gene, Your Alzheimer's Risk may be Doubled - HONOLULU, July 12 /PRNewswire-USNewswire/ -- A gene known as FTO, which appears to be correlated with obesity in humans, may also increase risk of Alzheimer's disease and dementia, according to new research presented today at the Alzheimer's Association International Conference on Alzheimer's Disease 2010 (AAICAD 2010) in Honolulu, HI. And when a person has certain variants of both FTO and a recognized...


Word of the Day
conjunto
  • A style of popular dance music originating along the border between Texas and Mexico, characterized by the use of accordion, drums, and 12-string bass guitar and traditionally based on polka, waltz, and bolero rhythms.
The word 'conjunto' comes through Spanish, from Latin coniūnctus, past participle of coniungere, to join together; see conjoin