Latest Amyloid precursor protein Stories
UC Irvine scientists have shown for the first time that neural stem cells can rescue memory in mice with advanced Alzheimer's disease, raising hopes of a potential treatment for the leading cause of elderly dementia that afflicts 5.3 million people in the U.S.Mice genetically engineered to have Alzheimer's performed markedly better on memory tests a month after mouse neural stem cells were injected into their brains. The stem cells secreted a protein that created more neural connections,...
Research carried out at the Hebrew University of Jerusalem has resulted in a promising approach to help treat Alzheimer's disease in a significant proportion of the population that suffers from a particularly rapid development of this disease.In the research at the Silberman Institute of Life Sciences of the Hebrew University, scientists solved a mystery as to why people who carried a mutated gene known as BChE-K were prone to more rapid development of Alzheimer's than those who had a normal...
A drug similar to one used in clinical trials for treatment of rheumatoid arthritis and psoriasis has been found to rescue memory in mice exhibiting Alzheimer's symptoms.The discovery by UC Irvine scientists offers hope that a new treatment may be on the horizon for people in the early stages of Alzheimer's, the leading cause of elderly dementia afflicting more than 5 million people in the U.S. and for which no cure exists.The drug, called PMX205, prevented inflamed immune cells from...
They say the findings cement relationship between the two brain disordersThe destructive cellular pathways activated in Alzheimer's disease are also triggered following traumatic brain injury, say researchers from Georgetown University Medical Center (GUMC). They say this finding suggests that novel therapy might successfully target both conditions.In an oral presentation at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease, the scientists will show that...
That morning cup of joe may help reverse memory loss in Alzheimer's patients.A new study shows caffeine significantly deceases abnormal levels of the protein linked to Alzheimer's disease in the brain and blood of mice that show symptoms of the disease.In the study, 55 mice were genetically altered to develop symptoms of Alzheimer's disease. After displaying signs of memory impairment, the mice were given the equivalent of five cups of coffee a day in their drinking water. After two months,...
MADISON, Wis., July 7 /PRNewswire/ -- In the midst of generally gloomy worldwide economic news and rising global tensions, an American neuroscience researcher has a message of hope: The answer for Alzheimer's disease and other degenerative diseases of the brain that cause memory loss may be much closer than we realize. Mark Underwood, president of the Madison, Wisconsin-based biotech company, Quincy Bioscience (www.quincybioscience.com), says several recent studies have confirmed a...
U.S. scientists say that drinking five cups of coffee a day could reverse memory problems seen in Alzheimer's disease, BBC News reported.Researchers also suggested that caffeine hampered the production of the protein plaques which are the hallmark of the disease, while studies in the past suggested a protective effect from caffeine.However, the study, which appears in the Journal of Alzheimer's Disease, does not conclude that dementia patients should start using caffeine supplements. A team...
U.S. scientists say a human growth factor used to stimulate blood stem cells to proliferate in bone marrow can also reverse memory impairment in mice. Researchers at the University of South Florida and Haley Hospital, both in Tampa, Fla., genetically altered mice to develop Alzheimer's disease. The scientists found the growth factor -- granulocyte-colony stimulating factor -- significantly reduced levels of the brain-clogging protein beta amyloid found in abundance in the brains of the...
Scientists at UC Santa Barbara and several other institutions have found laboratory evidence that a cluster of peptides may be the toxic agent in Alzheimer's disease. Scientists say the discovery may lead to new drugs for the disease.In an article published this week in Nature Chemistry, the researchers explain the process in which the toxic Amyloid Beta 42 peptides aggregate, and outline the new technology they use to study these peptides. The findings come out of the laboratory of Michael...
The new study shows GCSF impacts both bone marrow and brain to improve cognition A human growth factor that stimulates blood stem cells to proliferate in the bone marrow reverses memory impairment in mice genetically altered to develop Alzheimer's disease, researchers at the University of South Florida and James A. Haley Hospital found. The granulocyte-colony stimulating factor (GCSF) significantly reduced levels of the brain-clogging protein beta amyloid deposited in excess in the...
