Quantcast

Latest Amyloid precursor protein Stories

Unraveling Mysteries Of Amyloid Beta Peptides To Detect And Treat Alzheimer's Disease
2014-02-18 07:41:38

American Institute of Physics Alzheimer's disease has long been marked by progress -- but not the kind of progress the medical community seeks. It is the most common form of dementia among older Americans, and its risk increases with increasing age; for those living with the disease, its ravages get worse over time; and as we move into the 21st century, it will place a greater and greater burden on society. The number of Americans living with Alzheimer's has doubled since 1980 and is...

2014-01-20 12:26:21

Study uncovers role of Neuroligin-1 protein Cleveland Clinic researchers have identified a protein in the brain that plays a critical role in the memory loss seen in Alzheimer's patients, according to a study to be published in the journal Nature Neuroscience and posted online today. The protein – Neuroligin-1 (NLGN1) – is known to be involved in memory formation; this is the first time it's been linked to amyloid-associated memory loss. In Alzheimer's disease, amyloid beta...

2014-01-13 10:21:10

New Study Pinpoints Structural Effects of V44M and V44A Mutations New research, led by Rensselaer Polytechnic Institute researcher Chunyu Wang, has solved one mystery in the development of Familial Alzheimer’s Disease (FAD), a genetic variant of the disease that affects a small fraction of the Alzheimer’s population. In a paper published January 6 in the journal Nature Communications, Wang and his team follow the trail of two genetic mutations – V44M and V44A – known to cause FAD,...

Alzheimer’s Disease Tracked From The Beginning
2013-12-23 04:42:10

redOrbit Staff & Wire Reports - Your Universe Online By combining high-resolution functional MRI (fMRI) imaging scans in Alzheimer’s disease patients with mouse models of the neurodegenerative condition, researchers from Columbia University Medical Center (CUMC) have gained new insights into how, where and why the disease starts and spreads. The study, which was published Sunday in the online edition of Nature Neuroscience, will help enhance the medical community’s understanding...

2013-12-16 18:13:17

Massive neuron death that occurs in Alzheimer's appears to be caused by raw ingredients of plaques & tangles working in concert, rather than by plaques and tangles themselves Much of the debate in Alzheimer's disease (AD) has focused on whether the protein amyloid-beta or the tau protein is the symptom or the cause of the disease. But George Bloom, Ph.D., and colleagues at the University of Virginia (UVA) have pursued another hypothesis: much earlier interactions between the two...

Study Suggests Brain Blood Vessel Cells May Be Therapeutic Targets For Alzheimer's Disease
2013-12-13 14:28:51

NIH/National Institute of Neurological Disorders and Stroke A study in mice shows how a breakdown of the brain's blood vessels may amplify or cause problems associated with Alzheimer's disease. The results published in Nature Communications suggest that blood vessel cells called pericytes may provide novel targets for treatments and diagnoses. "This study helps show how the brain's vascular system may contribute to the development of Alzheimer's disease," said study leader Berislav V....

2013-11-11 21:27:19

Patients with traumatic brain injury (TBI) had increased deposits of β-Amyloid (Aβ) plaques, a hallmark of Alzheimer Disease (AD), in some areas of their brains in a study by Young T. Hong, Ph.D., of the University of Cambridge, England, and colleagues. There may be epidemiological or pathophysiological (changes because of injury) links between TBI and AD, and Aβ plaques are found in as many as 30 percent of patients who die in the acute phase after a TBI. The plaques appear within...

2013-10-17 17:14:11

A new technique allows researchers to activate proteins in the brain by shining an LED light on them With the flick of a light switch, researchers at the Salk Institute for Biological Studies can change the shape of a protein in the brain of a mouse, turning on the protein at the precise moment they want. This allows the scientists to observe the exact effect of the protein's activation. The new method, described in the October 16 issue of the journal Neuron, relies on specially engineered...

2013-09-23 23:26:46

Two rare mutations in the human gene that lead to the most common, late-onset variant of Alzheimer's have been identified by Chair Member of the Cure Alzheimer's Disease Research Consortium, Dr. Rudy Tanzi, bringing researchers closer to identifying a cure. Boston, MA (PRWEB) September 23, 2013 In a paper recently published in the prestigious journal Neuron, Harvard Medical School/Mass General Hospital Geneticist Dr. Rudy Tanzi, together with lead author, Dr. Jaehong Suh and their...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
Related