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Latest Amyloid precursor protein Stories

Tiny Molecule May Help Treat Alzheimers
2013-06-27 12:23:53

Brett Smith for redOrbit.com - Your Universe Online Researchers at Northwestern University say they have been working with a promising new drug-like molecule that could lead to a preventative treatment for Alzheimer's disease, according to their report in the open access journal PLOS ONE. "This is the starting point for the development of a new class of drugs," said lead researcher D. Martin Watterson, a professor molecular biology and biochemistry at Northwestern. "It's possible...

2013-06-24 10:37:13

Researchers in Berlin and Munich, Germany and Oxford, United Kingdom, have revealed that a protein well known for its role in Alzheimer's disease controls spindle development in muscle and leads to impaired movement in mice when the protein is absent or treated with inhibitors. The results, which are published in The EMBO Journal, suggest that drugs under development to target the beta-secretase-1 protein, which may be potential treatments for Alzheimer's disease, might produce unwanted side...

Alzheimer's Disease Drug Stopped Mid-Trial
2013-06-17 05:08:38

Lee Rannals for redOrbit.com - Your Universe Online Eli Lilly & Co has ended a clinical trial for an Alzheimer's disease drug during the middle of the study after patients showed abnormal liver biochemical tests. The company announced last week that it would be putting a halt to its LY2886721 drug trial. LY2886721, the code-name for the drug, was designed to inhibit beta secretase, which contributes to the buildup of amyloid plaque in the brain that is believed to cause Alzheimer's....

2013-05-29 10:13:32

Scientists at the University of Liverpool and Callaghan Innovation in New Zealand have developed a new chemical approach to help harness the natural ability of complex sugars to treat Alzheimer's disease. The team used a new chemical method to produce a library of sugars, called heparan sulphates, which are known to control the formation of the proteins in the brain that cause memory loss. Heparan sulphates are found in nearly every cell of the body, and are similar to the natural...

Researchers Slow Alzheimer's, Improve Memory In Mice Using Novel Drug
2013-05-14 16:02:24

Brett Smith for redOrbit.com - Your Universe Online Many Alzheimer´s disease researchers are focused on stopping the buildup of amyloid plaques, dense protein deposits that are a telltale sign of the debilitating disease. However, a group of scientists from the Salk Institute for Biological Studies decision to think outside the box and pursue a different treatment strategy has paid off. According to their report in the journal Alzheimer´s Research and Therapy, the Salk team...

Alzheimer's Disease: Protective Gene Variant Sheds Light On Potential New Treatment
2013-04-26 04:44:04

redOrbit Staff & Wire Reports - Your Universe Online New research published Thursday in the journal Neuron sheds new light on the molecular causes of Alzheimer´s disease, while also revealing a potential new therapy which could help prevent cognitive decline and brain damage during the early stages of the neurodegenerative disorder. The study focuses on a variant of a gene known as CD33, which typically contributes to Alzheimer´s disease by inhibiting the ability of a...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'