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Latest Amyloid precursor protein Stories

2012-04-10 13:50:29

According to new study published in the Journal of Alzheimer's Disease Alzheimer's disease (AD) is now the sixth leading cause of death among Americans, affecting nearly 1 in 8 people over the age of 65. There is currently no treatment that alters the course of this disease. However, an increasing amount of evidence suggests that changes in the way the body handles iron and other metals like copper and zinc may start years before the onset of AD symptoms. A new study shows that reducing...

2012-04-10 12:25:54

According to new study published in the Journal of Alzheimer´s Disease Alzheimer´s disease (AD) is now the sixth leading cause of death among Americans, affecting nearly 1 in 8 people over the age of 65. There is currently no treatment that alters the course of this disease. However, an increasing amount of evidence suggests that changes in the way the body handles iron and other metals like copper and zinc may start years before the onset of AD symptoms. A new study shows that...

2012-04-04 11:01:20

Discovery challenges current thinking and points to new therapies Scientists at the Gladstone Institutes have enhanced our understanding of how a protein linked to Alzheimer's disease keeps young brains healthy, but can damage them later in life–suggesting new research avenues for treating this devastating disease. In the Journal of Neuroscience, available online today, researchers in the laboratory of Yadong Huang, MD, PhD, have uncovered the distinct roles that the apoE protein...

2012-03-29 23:20:41

Findings target disease-causing tau isoform and raise the possibility of an immunization strategy at early stage of disease Under normal circumstances, the tau protein is a hard-working participant in memory and normal brain functioning. But as is becoming increasingly evident, in Alzheimer's disease and other neurodegenerative diseases, tau not only ceases to play a productive role in brain health, but actually undergoes a Jekyll-and-Hyde transformation to become a misshapen villain that...

2012-03-12 10:18:28

Researchers presenting talks at the Genetics Society of America's 53rd Annual Drosophila Research Conference in Chicago present new information on topics from neural diseases to kidney stones More than two-thirds of human genes have counterparts in the well-studied fruit fly, Drosophila melanogaster, so although it may seem that humans don't have much in common with flies, the correspondence of our genetic instructions is astonishing. In fact, there are hundreds of inherited diseases in...

2012-03-08 01:03:09

Researchers at the University of California, San Diego, the Medical University of South Carolina, the University of Cincinnati, and American Life Science Pharmaceuticals of San Diego have validated the protease cathepsin B (CatB) as a target for improving memory deficits and reducing the pathology of Alzheimer's disease (AD) in an animal model representative of most AD patients. The study has been published in the online edition of the Journal of Alzheimer's Disease. According to...

2012-03-07 11:15:03

Antibodies that block the process of synapse disintegration in Alzheimer's disease have been identified, raising hopes for a treatment to combat early cognitive decline in the disease. Alzheimer's disease is characterized by abnormal deposits in the brain of the protein Amyloid-ß, which induces the loss of connections between neurons, called synapses. Now, scientists at UCL have discovered that specific antibodies that block the function of a related protein, called Dkk1,...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.