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Latest Anaplastic lymphoma kinase Stories

2012-08-13 15:50:34

A broken chromosome is like an unmoored beansprout circling in search of attachment. If a cell tries to replicate itself with broken chromosomes, the cell will be killed and so it would very much like to find its lost end. Often, it finds a workable substitute: another nearby chromosome. When a broken chromosome attaches to another, or when chromosomes use a similar process to exchange genetic material, you have a translocation — genes end up fused to other genes, encoding a new...

2012-07-11 14:47:35

A new drug combination could offer hope to children with neuroblastoma — one of the deadliest forms of childhood cancer — by boosting the effectiveness of a promising new gene-targeted treatment. Researchers at The Institute of Cancer Research in London have found a way to overcome the resistance of cancer cells to a drug called crizotinib, which recently showed positive early results in its first trial in children with cancer. Crizotinib has already been licensed by the US...

2012-05-17 12:14:34

Children's Hospital of Philadelphia researcher leads trial of ALK inhibitor in neuroblastoma, lymphoma A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma. A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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