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Last updated on April 17, 2014 at 11:11 EDT

Latest Angiogenesis inhibitor Stories

2014-01-21 10:21:17

Cancer cells have something that every prisoner longs for—a master key that allows them to escape. A study in The Journal of Cell Biology describes how a protein that promotes tumor growth also enables cancer cells to use this key and metastasize. Unless it can enter a blood or lymphatic vessel, a cancer cell is imprisoned in the tissue where it arises. The growth factor VEGF is the tumor cell's master key. It loosens connections between endothelial cells that form the lining of blood...

2013-11-29 14:37:54

A study led by researchers at Boston University School of Medicine (BUSM) demonstrates a new mechanism involving a signaling protein and its receptor that may block the formation of new blood vessels and cancer growth. The findings are published in the December issue of Science Signaling. Angiogenesis creates new blood vessels in a process that can lead to the onset and progression of several diseases such as cancer and age-related macular degeneration. Vascular endothelial growth...

2013-09-28 08:20:17

AMSTERDAM, Sept. 28, 2013 /PRNewswire/ -- The Angiogenesis Foundation released a white paper at the 2013 European Cancer Congress that addresses the needs, challenges, and proposed solutions for improving treatment of metastatic colorectal cancer (mCRC), the third most common cancer among men and the second most common among women worldwide. The white paper, "Improving Outcomes in the Treatment and Management of Metastatic Colorectal Cancer," is the result of the International Expert...

2013-06-25 23:01:51

BerriProducts LLC, an Oregon-based supplier of premium quality black raspberry products shares news from the recently-attended Berry Health Benefits Symposium on angiogenesis inhibition with an in vitro test on human carcinoid cancer cells Charlotte, North Carolina (PRWEB) June 25, 2013 Dr. Eugene Woltering, Section Chief of Surgical Endocrinology at the Louisiana State University Health Sciences Center in New Orleans presented some results of his work on neuroendocrine tumors (NETS)....

2013-06-03 10:43:06

Gene panel may help personalize therapy for aggressive brain tumors A new test may help identify newly diagnosed glioblastoma patients more likely to benefit from bevacizumab (Avastin®), according to new research from The University of Texas MD Anderson Cancer Center. The results of the study were presented today at the annual meeting of the American Society of Clinical Oncology. This study is associated with RTOG 0825, a large multi-center Phase III trial that evaluated the...

2013-05-31 08:24:48

CHICAGO, May 31, 2013 /PRNewswire/ -- The Angiogenesis Foundation will release two new white papers, in conjunction with the American Society of Clinical Oncology (ASCO) Annual Meeting, which address the needs, challenges, and proposed solutions to improve outcomes in two of the top ten most common cancers in the United States: metastatic colorectal cancer (mCRC) and renal cell carcinoma (RCC), also known as kidney cancer. The white papers, "Advancing Outcomes for the Treatment of Metastatic...

2013-05-22 10:20:47

Study clarifies roles of anti-angiogenic proteins in discouraging metastasis and reveals potential anti-metastasis drug By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer. The findings suggest that a prosaposin-based drug could potentially block...

2013-05-21 16:27:44

Study clarifies roles of anti-angiogenic proteins in discouraging metastasis and reveals potential anti-metastasis drug BOSTON, May 21, 2013 /PRNewswire-USNewswire/ -- By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer. The findings suggest that...

2013-05-05 16:20:25

CAMBRIDGE, Mass., May 5, 2013 /PRNewswire/ -- The Angiogenesis Foundation released a new white paper, "Advocating for Improved Treatment and Outcomes for Wet Age-Related Macular Degeneration" (AMD). Wet AMD is the most common form of blindness in people 50 years or older in developed nations. The report is based on the Australian Wet Age-Related Macular Degeneration Coalition Expert Summit convened in Sydney, Australia last July by the Angiogenesis Foundation and Macular Degeneration...

2013-04-22 11:22:53

A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma. In a paper published in the April 19 issue of Molecular Cancer Therapeutics, a team led by Nancy Klauber-DeMore, MD, professor of surgery and a member of UNC Lineberger Comprehensive Cancer Center, used a monoclonal antibody to target SFRP2 expressed in cells from triple-negative breast...