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Latest Angiogenesis inhibitor Stories

2014-05-07 09:54:08

Mechanisms of VEGF inhibitor-induced hypertension need to be better understood and guidelines developed to improve management, say researchers in the Canadian Journal of Cardiology New cancer therapies, particularly agents that block vascular endothelial growth factor (VEGF) signaling, have improved the outlook for patients with some cancers and are now used as a first line therapy for some tumors. However, almost 100% of patients who take VEGF inhibitors (VEGFIs) develop high blood...

2014-01-21 10:21:17

Cancer cells have something that every prisoner longs for—a master key that allows them to escape. A study in The Journal of Cell Biology describes how a protein that promotes tumor growth also enables cancer cells to use this key and metastasize. Unless it can enter a blood or lymphatic vessel, a cancer cell is imprisoned in the tissue where it arises. The growth factor VEGF is the tumor cell's master key. It loosens connections between endothelial cells that form the lining of blood...

2013-11-29 14:37:54

A study led by researchers at Boston University School of Medicine (BUSM) demonstrates a new mechanism involving a signaling protein and its receptor that may block the formation of new blood vessels and cancer growth. The findings are published in the December issue of Science Signaling. Angiogenesis creates new blood vessels in a process that can lead to the onset and progression of several diseases such as cancer and age-related macular degeneration. Vascular endothelial growth...

2013-06-25 23:01:51

BerriProducts LLC, an Oregon-based supplier of premium quality black raspberry products shares news from the recently-attended Berry Health Benefits Symposium on angiogenesis inhibition with an in vitro test on human carcinoid cancer cells Charlotte, North Carolina (PRWEB) June 25, 2013 Dr. Eugene Woltering, Section Chief of Surgical Endocrinology at the Louisiana State University Health Sciences Center in New Orleans presented some results of his work on neuroendocrine tumors (NETS)....

2013-06-03 10:43:06

Gene panel may help personalize therapy for aggressive brain tumors A new test may help identify newly diagnosed glioblastoma patients more likely to benefit from bevacizumab (Avastin®), according to new research from The University of Texas MD Anderson Cancer Center. The results of the study were presented today at the annual meeting of the American Society of Clinical Oncology. This study is associated with RTOG 0825, a large multi-center Phase III trial that evaluated the...

2013-05-22 10:20:47

Study clarifies roles of anti-angiogenic proteins in discouraging metastasis and reveals potential anti-metastasis drug By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer. The findings suggest that a prosaposin-based drug could potentially block...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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