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Latest Angiogenesis inhibitor Stories

2010-01-11 13:14:45

Researchers at Karolinska Institutet have discovered a new way of blocking the formation of blood vessels and halting the growth of tumors in mice. A substance that exploits this mechanism could be developed into a new treatment for cancer. For a cancer tumor to be able to grow larger than the size of a pea, the cancer cells need to stimulate the formation of new blood vessels that can supply the tumor with oxygen and nutrients, a process known as angiogenesis. A number of medicines which...

2009-11-11 17:27:26

Researchers at Uppsala University, in collaboration with colleagues in Sweden and abroad, have identified an entirely new mechanism by which a specific protein in the body inhibits formation of new blood vessels. Inhibiting the formation of new blood vessels is an important aspect of, for example, cancer treatment. The study is published in the November issue of the journal Molecular Cancer Research. Angiogenesis, the formation of new blood vessels, is strictly regulated by a number of...

2009-11-03 10:04:00

NEW YORK, Nov. 3 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue. Chinese Markets for Brain Cancer Treatment Drugs http://www.reportlinker.com/p0157400/Chinese-Markets-for-Brain-Cancer-Treatment-Drugs.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=prnewswire China's demand for Brain Cancer Treatment Drugs has grown at a fast pace in the past decade. In the next five years, both production and demand will continue...

2009-08-26 14:12:10

In new animal research done by investigators at Wake Forest University School of Medicine, scientists have discovered a treatment effective in mice at blocking the growth and shrinking the size of lung cancer tumors, one of the leading causes of cancer death in the world.The study, recently published in Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research, is the first to show that treatment with a specific peptide, angiotensin-(1-7), reduces lung tumor...

2009-07-16 10:35:04

Prognosis of pancreatic cancer is poor. Recently, it has been clarified that the grade of tumor angiogenesis is a useful prognostic marker in human cancer, including pancreatic cancer. To establish the grade of tumor angiogenesis by non-invasive imaging may be important clinically. However, there are only a few such reports on pancreatic cancer.The present study, lead by Dr. Hattori and her colleagues from Kanazawa University Graduate School of Medical Science, has recently been published on...

2009-07-15 08:14:46

Endothelial progenitor cells may play a role in the start and progression of metastatic disease in children with cancer, according to study results published in Clinical Cancer Research, a journal of the American Association for Cancer Research."This is the first study to measure circulating endothelial cells and endothelial progenitor cells in children with cancer, which can provide insight as to the biology of their tumor vessels," said researcher Françoise Farace, Ph.D.,...

2009-07-08 16:57:54

Treatment with the angiogenesis inhibitor bevacizumab improved hearing and alleviated other symptoms in patients with neurofibromatosis type 2 (NF2). In a paper to appear in the July 23 New England Journal of Medicine, which is receiving early online release, researchers from Massachusetts General Hospital (MGH) report that bevacizumab treatment successfully shrank characteristic tumors in a small group of NF2 patients, the first reported successful NF2 treatment not involving surgery or...

2009-06-23 12:53:09

A report in Cancer Research, a journal of the American Association for Cancer Research, highlights a new biomarker that may be useful in identifying patients with recurrent glioblastoma, or brain tumors, who would respond better to anti-vascular endothelial growth factor therapy, specifically cediranib.Cediranib is a highly potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases. It is an investigational, oral agent that is administered once daily. Using a form...

2009-06-09 13:44:30

 To grow and spread, tumors need new blood vessels, a process called angiogenesis. One growth factor that causes angiogenesis has been identified -  vascular endothelial growth factor or  VEGF - and drugs to inhibit VEGF are already in use. But not all tumors respond to the therapy initially or over the long term. Thus new growth factors need to be identified to aid in developing the next generation of angiogenesis inhibitors.Scientists at the UNC Lineberger Comprehensive...

2009-03-30 14:38:20

U.S. medical researchers say the positive effects of anti-angiogenesis drugs in treating brain tumors appears to result from edema reduction. The Massachusetts General Hospital scientists said the reduction in size of the brain tumors, called glioblastomas, appears to result primarily from reduction of the swelling of brain tissue and not from any direct anti-tumor effect. Angiogenesis is the formation of new blood vessels. The study involved treatment with the experimental drug cediranib and...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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