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Latest Angiogenesis Stories

2012-01-25 12:38:01

Finding could explain limited success of anti-angiogenesis treatments in breast cancer Cancer treatments designed to block the growth of blood vessels were found to increase the number of cancer stem cells in breast tumors in mice, suggesting a possible explanation for why these drugs don't lead to longer survival, according to a new study by researchers at the University of Michigan Comprehensive Cancer Center. The drugs Avastin and Sutent have been looked at as potential breast cancer...

2012-01-18 06:29:54

(Ivanhoe Newswire) — A new study found that a group of little-explored cells in the tumor microenvironment can likely serve as gatekeepers against cancer progression and metastasis. One known way of treating cancer is by targeting angiogenesis, or blood vessel growth. Raghu Kalluri, MD, PhD, Chief of the Division of Matrix Biology at Beth Israel Deaconess Medical Center (BIDMC) and Professor of Medicine at Harvard Medical School (HMS) and colleagues, hypothesized whether targeting a...

2012-01-18 00:07:26

Paradoxical discovery finds that a group of cells known as pericytes help prevent metastasis A new study finds that a group of little-explored cells in the tumor microenvironment likely serve as important gatekeepers against cancer progression and metastasis. Published in the January 17 issue of Cancer Cell, these findings suggest that anti-angiogenic therapies — which shrink cancer by cutting off tumors' blood supply — may inadvertently be making tumors more aggressive and...

2012-01-17 22:38:41

New research explains how cells regulate their bonds during the development of new blood vessels. For the first time, the role of the protein Raf-1 in determining the strength of the bond between cells has been shown. If Raf-1 is not present, the cells cannot stick together and the formation of new blood vessels is inhibited. This discovery may one day lead to new approaches to cancer treatment. Angiogenic sprouting, the process by which new blood vessels grow from existing vessels, is a...

2012-01-10 21:26:40

Researchers at Linköping University are now launching a plan to effectively treat psoriasis. About 300 000 Swedes suffer from the difficult to treat disease, which manifests itself in scaly and often itchy patches on the skin. The reason is that cells divide without restraint as new blood vessels form in the deeper layers of the skin. An important component is the psoriasin protein (S100A7), which are abundant in psoriasis-affected skin but rarely in normal skin. The same...

2011-12-21 06:24:22

(Ivanhoe Newswire) — Scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth. Cancer cells can grow and multiply faster by creating their own blood vessels. Cancer cells gain the nutrients they need by producing proteins that make blood vessels grow, helping deliver oxygen and sugars to the tumor. These proteins are vascular growth factors like VEGF – the target for the anti-cancer drug Avastin. Making these...

2011-12-19 16:05:38

Recent findings in mice suggest that blocking the production of small molecules produced in the body, known as epoxyeicosatrienoic acids (EETs), may represent a novel strategy for treating cancer by eliminating the blood vessels that feed cancer tumors. This research is the first to show that EETs work in concert with vascular endothelial growth factor (VEGF), a protein known to induce blood vessel growth. Together, EETs and VEGF promote metastasis, or the spread of cancer, by encouraging the...

2011-12-19 15:06:25

Study documents connection between increased levels of these lipids and cancer growth and metastasis; also opens door to new avenue for cancer treatment A group of small molecules called EETs — currently under scrutiny as possible treatment targets for a host of cardiovascular diseases — may also drive the growth and spread of cancer, according to researchers at the Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) and other institutions. Their findings also raise the...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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