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Latest Angiogenesis Stories

2011-04-11 21:44:32

Angiogenesis, the development of new blood vessels, is required during embryonic development and wound healing, as well as during disease processes such as tumor growth. The signals that direct angiogensis are incompletely understood, but could represent novel targets for the development of therapies that promote or inhibit this process. In this paper, Young-Guen Kwon and colleagues, of Yonsei University in Seoul, Korea, investigated the role of two related proteins- DKK1 and DKK2- in...

2011-04-06 06:30:00

MELBOURNE, Australia, April 6, 2011 /PRNewswire/ -- Circadian Technologies (ASX.CIR) announced today that its licensee ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company, has advised that it has commenced the first Phase 1 clinical trial of its fully-human monoclonal antibody IMC-3C5. IMC-3C5 is a fully-human IgG1 monoclonal antibody being developed by ImClone as a treatment for cancer. ImClone has exclusive rights from Circadian's 100%-owned subsidiary Vegenics to...

2011-04-06 06:30:00

MELBOURNE, Australia , April 6, 2011 /PRNewswire/ -- Data demonstrates efficacy of VGX-100 with other therapeutic agents in mouse models of lung, ovarian and prostate cancers. VGX-100 improves the efficacy of Avastin® in a lung cancer model and further inhibits tumour growth when combined with Avastin® plus docetaxel in mouse models of human lung and ovarian cancer. Data expand on previous anti-cancer effects seen with VGX-100 in prostate, pancreatic...

2011-04-05 14:03:19

Scientists from the School of Pharmacy at Queen's University Belfast and Almac Discovery Ltd have developed a new treatment for cancer which rather than attacking tumors directly, prevents the growth of new blood vessels in tumors, starving them of oxygen and nutrients, thereby preventing their growth. Targeting tumor blood vessels is not a new concept, however, this drug attacks the blood vessels using an entirely different pathway and therefore could be useful for treating tumors which...

2011-04-04 05:05:00

CRAIGAVON, Northern Ireland, April 4, 2011 /PRNewswire/ -- - Scientists at Almac and Queen's University Belfast Discover Novel Approach to Treat Cancer Patients New Study findings published in Clinical Cancer Research - The Journal of the American Association of Cancer Research (AACR) Scientists from the School of Pharmacy at Queen's University Belfast and Almac Discovery Ltd, announce the first publication describing a potential new anti-angiogenic therapy based on a...

2011-03-28 13:59:00

Major Scientific and Clinical Conference to Take Place August 2011 CHICAGO, March 28, 2011 /PRNewswire-USNewswire/ -- The American College of Wound Healing and Tissue Repair (ACWHTR) is a non-profit organization founded by faculty from the University of Illinois at Chicago (UIC) and the Angiogenesis Foundation (Cambridge, MA) in 2010. Created to develop a formal, clinically-based, educational curriculum in wound healing for physicians, the goal of the ACWHTR is to bring the practice of...

2011-03-10 16:06:03

UNC researchers have discovered that a molecule called Wnt1 can improve the function of endothelial progenitor cells, increasing the blood flow to organs that previously had been cut off from the circulation. Circulating through the bloodstream of every human being is a rare and powerful type of cell, one that can actually create new blood vessels to bypass blockages that cause heart attacks and peripheral artery disease. Though everyone has these cells "“ called endothelial progenitor...

2011-03-08 02:51:54

Great deal of variation found in behavior of genetically identical cells -- noise may be a clue Biologists tend to look at cells in bulk, observing them as a group and taking the average behavior as the norm "” the assumption is that genetically identical cells all behave the same way. In a paper to be published in the online Early Edition of Proceedings of the National Academy of Sciences the week of March 7, 2011, Sam Sia, assistant professor of biomedical engineering at Columbia...

2011-03-03 16:51:46

Researchers have synthesized the vast literature on cancer to produce a next-generation view of the features that are shared amongst all cancer cells. These hallmarks of the disease provide a comprehensive and cohesive foundation for the field that will influence biomedical researchers in their quest for new cancer treatments. The review article by Douglas Hanahan of Ó°cole Polytechnique F©d©rale in Switzerland and Robert Weinberg of the Whitehead Institute...

2011-02-25 13:17:45

European Multidisciplinary Conference in Thoracic Oncology news A drug that is currently used to help treat bone metastases in patients with lung cancer could also be useful at an earlier stage of treatment, to prevent the cancer from spreading in the first place, Italian researchers have found. Dr Michela Quirino and colleagues from the Catholic University of the Sacred Heart in Rome have reported important new evidence that zoledronic acid may be able to prevent lung cancer metastases from...