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Last updated on April 16, 2014 at 21:24 EDT

Latest Angiogenesis Stories

2013-04-02 12:30:07

DUBLIN, April 2, 2013 /PRNewswire/ -- Research and Markets) has announced the addition of the "Vascular Endothelial Growth Factor (VEGF) Inhibition: Therapy-Indicating and Prognostic Biomarkers, 2013" report to their offering      (Logo: http://photos.prnewswire.com/prnh/20130307/600769 ) Vascular Endothelial Growth Factor (VEGF), which plays an important role in angiogenesis, has been extensively studied and over-expression is seen in many cancers. Today, VEGF is...

2013-03-28 00:20:58

TOKYO, March 28, 2013 /PRNewswire/ -- Anaeropharma Science Inc. announced on March 28 that it has initiated a Phase I clinical trial of APS001F in patients with advanced solid tumors in the United States. The first-in-human dose-escalation trial enrolls patients with advanced and/or metastatic solid tumors whose disease is no longer considered responsive to available treatments. The trial is designed to evaluate safety, tolerability and efficacy of the study agent. About...

2013-03-21 08:30:06

ROCKVILLE, Md., March 21, 2013 /PRNewswire/ -- EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer, today reported results for the three months and twelve months ended December 31, 2012. (Logo: http://photos.prnewswire.com/prnh/20010620/ENMDLOGO ) The Company reported a net loss of ($0.4 million), or ($0.02) per share for the three months ended December 31, 2012. This compares with net income of $1.0 million, or $0.06...

2013-03-18 12:28:02

Markers such as CA9, CD31, CD34 and VEGFR1/2 in the primary tumors might serve as predictors of a good response to a sunitinib treatment in patients with metastatic clear cell renal cell carcinoma (ccRCC), according to a new study to be presented at the 28th Annual EAU Congress currently on-going in Milan. "The inactivation of the von Hippel-Lindau gene (VHL) is a common event in ccRCC and finally leads to the induction of HIF1α target genes such as CA9 and VEGF," write the...

2013-03-13 17:50:29

Following several years of study, investigators have found more evidence that viral therapy to treat solid tumors can be enhanced by blocking the body´s natural immune response. Oncolytic viruses have shown promise as anticancer agents, with variations of the herpes simplex virus (HSV) among the most commonly used. However, many studies have shown that the effectiveness of viral therapy to eradicate tumors has not been as successful with patients as it has been in the lab. These...

2013-03-05 10:56:48

Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected — and critical — additional role in cancer metastasis in a study conducted collaboratively in the labs of Karen Lounsbury, Ph.D., University of Vermont professor of pharmacology, and Christopher Francklyn, Ph.D., UVM professor of biochemistry. The group determined that threonyl tRNA synthetase (TARS) leads a "double...

2013-03-05 08:30:03

Data Demonstrate Increased Blood Flow and Vasculogenesis in Models of Ischemic Stroke and Peripheral Vascular Disease CAMBRIDGE, Mass., March 5, 2013 /PRNewswire/ -- Tarix Pharmaceuticals, a biopharmaceutical company focused on developing novel, peptide-based therapies to treat a range of critical medical conditions, today announced it has uncovered a new role for its therapeutic peptides in stimulating revascularization following ischemia. In models of ischemic stroke and...

2013-03-01 08:24:44

ROCKVILLE, Md., March 1, 2013 /PRNewswire/ -- EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer, announced today that it has received commitments from investors, including institutional investors Kleiner Perkins Caufield Byers China Fund II, L.P. and IDG-Accel China Growth Fund III L.P. to purchase approximately $10.7 million of securities in a registered direct offering. EntreMed expects to receive net proceeds of...

2013-02-11 13:31:42

A lack of the protein endoglin in the blood vessels of tumor-bearing mice enables the spread of daughter tumors, according to researchers at Karolinska Institutet and Lund University in Sweden in a study published in the scientific periodical The Journal of Experimental Medicine. Given that the tumor vasculature constitutes an important barrier to the spread of cancer cells, the team suggests that drugs should be developed to strengthen the blood vessels' protective function. Studies of...

How Blood Vessels Regroup After Stroke
2013-02-11 10:53:18

Rice University [ Watch The Video ] By thinking of cells as programmable robots, researchers at Rice University hope to someday direct how they grow into the tiny blood vessels that feed the brain and help people regain functions lost to stroke and disease. Rice bioengineer Amina Qutub and her colleagues simulate patterns of microvasculature cell growth and compare the results with real networks grown in their lab. Eventually, they want to develop the ability to control the way...