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Latest Animal physiology Stories

2011-12-12 12:49:52

Researchers at the Stanford University School of Medicine report that they have identified the molecular pathway through which physical force contributes to scarring in mice. "Our study exposes one of the fundamental mechanisms by which the mechanical environment can directly increase inflammation, which is strongly implicated in scarring," said Geoffrey Gurtner, MD, professor and associate chair of surgery. Mice genetically engineered to lack an enzyme that is activated by mechanical...

2011-11-23 12:09:07

Two out of every thousand babies are at risk of brain damage in connection with birth. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have identified mechanisms behind these injuries, which could lead to better treatment and a richer life for the infants affected. Roughly two in every thousand babies are at risk of suffering brain damage as a result of events before, during and after delivery. Infections in the blood or a reduced supply of oxygen and blood can...

2011-10-12 22:52:06

In an advance toward eliminating pockets of infection in the brain that help make HIV disease incurable, scientists report the development of new substances that first plug the biological vacuum cleaner that prevents anti-HIV drugs from reaching the brain and then revert to an active drug to treat HIV. They describe the advance, which allows medications to cross the so-called "blood-brain barrier" (BBB) and treat brain diseases, in the Journal of the American Chemical Society. Jean...

2011-10-10 09:01:14

Researchers find pathway to potentially block disease-inducing inflammation Researchers have discovered a cellular pathway that promotes inflammation in diseases like asthma, rheumatoid arthritis, psoriasis, inflammatory bowel disease, and multiple sclerosis. Understanding the details of this pathway may provide opportunities for tailored treatments of inflammatory and autoimmune diseases. Discovery of this pathway was the work of an active collaboration between Xiaoxia Li, Ph.D., and...

Asian Elephants Ride Out High Daytime Temperatures
2011-09-30 10:15:37

Scientists at the University of Veterinary Medicine, Vienna´s Research Institute of Wildlife Ecology have discovered the mechanism by which Asian elephants are able to tolerate hot daytime temperatures.  Their results are published in the current issue of the international Journal of Comparative Physiology B. The heat is on where elephants roam.  Daytime temperatures in the natural environment of Asian elephants (Elephas maximus) average between 30 and 35 degrees...

2011-09-19 23:33:19

By using a mouse model of inflammation researchers at the University of Calgary have discovered a new class of molecules that can inhibit the recruitment of some white blood cells to sites of inflammation in the body. A provisional patent has been filed on these molecules by Innovates Calgary. When there is inflammation in the body, one of the primary defense mechanisms is the movement of white blood cells, known as neutrophils, from the bloodstream into the infected tissue. Neutrophils...

2011-09-19 23:26:33

New technique offers safe and noninvasive drug delivery to the brain regions affected by diseases such as Alzheimer's, Parkinson's, ALS, epilepsy and more Columbia Engineering researchers have developed a new technique to reach neurons through the blood-brain barrier (BBB) and deliver drugs safely and noninvasively. Up until now, scientists have thought that long ultrasound pulses, which can inflict collateral damage, were required. But in this new study, the Columbia Engineering team show...

2011-09-14 11:39:45

Researchers may have solved 100-year-old puzzle Cornell University researchers may have solved a 100-year puzzle: How to safely open and close the blood-brain barrier so that therapies to treat Alzheimer's disease, multiple sclerosis and cancers of the central nervous system might effectively be delivered. (Journal of Neuroscience, Sept. 14, 2011.) The researchers found that adenosine, a molecule produced by the body, can modulate the entry of large molecules into the brain. For the...

2011-07-20 17:05:26

Researchers discover brain chemical that causes strange, serious complication For hundreds of thousands of people, injuring a muscle through an accident like falling off a bike or having surgery can result in a strange and serious complication. Their muscles start growing bones. No one understood what caused the abnormal bone growth, so there was no treatment. But now, research from Northwestern University Feinberg School of Medicine and the Perelman School of Medicine at the University of...

2011-07-19 11:20:00

HARRISBURG, Pa., July 19, 2011/PRNewswire-USNewswire/ -- With "feels-like" temperatures approaching or exceeding 100 degrees forecast for parts of Pennsylvania this week, the Department of Health is reminding all Pennsylvanians of important steps they can take to protect their health. "According to the National Weather Service, afternoon heat indices may reach 100 degrees - and possibly higher - between Thursday and Saturday," said Health Secretary Dr. Eli Avila. "We are encouraging all...