Quantcast

Latest Anti-citrullinated protein antibody Stories

2009-10-20 07:05:00

ABBOTT PARK, Ill., Oct. 20 /PRNewswire-FirstCall/ -- An important assay used to aid in the diagnosis of rheumatoid arthritis (RA) will soon be available on Abbott's ARCHITECT immunoassay analyzers. The FDA has granted 510(k) clearance for an antibody cyclic-citrulinated peptide, or anti-CCP assay, to run on the world class systems. Many patients with RA develop an immune response against proteins containing citrulline long before they present symptoms of the disease. Studies show...

2009-06-16 13:40:00

Researchers in France suggest that the season in which rheumatoid arthritis symptoms appear may indicate the severity of those symptoms. The findings, presented in Copenhagen at the annual congress of the European League Against Rheumatism, may help identify patients with rheumatoid arthritis needing more intensive early therapy. Study leader Dr. Gael Mouterde of Lapeyronie Hospital in Montpellier, France, said patients whose first symptoms occur in winter had greater erosion and joint...

2009-06-12 11:10:03

Anti-TNF therapy can improve periodontal status after 6 months Over half (56%) of people with rheumatoid arthritis (RA) also have periodontitis (a chronic inflammatory disease of the gum and surrounding ligaments and bones that hold the teeth in place), displaying fewer teeth than healthy matched controls, high prevalence of oral sites presenting dental plaque and advanced attachment loss (the extent of periodontal support that has been destroyed around a tooth) (chi square p<0.05),...

2009-06-12 10:22:12

When a patient's first symptoms of rheumatoid arthritis (RA) occur in winter, the severity of their RA (as measured by the modified Total Sharp Score, mTSS, an assessment of erosion and joint space narrowing) was rated more severe at six months, when compared to patients whose RA first became symptomatic in summer (Odds Ratio (OR) =2.82 [1.14;7], p=0.0255). Furthermore, RA patients with their first symptoms in spring showed poorer radiographic outcome compared to summer-onset patients...

2009-06-02 08:09:04

Recent genetic studies have revealed several new sites of genes that are risk factors for developing rheumatoid arthritis (RA). The strongest association with anti-citrullinated protein antibody (ACPA)-positive RA (ACPAs are autoantibodies detected in RA that are used as a major diagnostic tool) has been found for the HLA-DRB1 gene, and this site seems to play a central role in susceptibility to the disease in Caucasian populations. Previous studies have shown a high increase in the risk of...

2009-04-06 03:28:00

BANGKOK, April 6 /PRNewswire/ -- Rheumatoid arthritis (RA) is a systemic disease or an autoimmune disorder in which the body's defense system attacks the joints through the thin layer of cells called the synovium that lines and lubricates the joints. The most visible symptoms of RA are swollen joints and crippling stiffness, particularly of the hands and feet. It can cause fatigue, fever, loss of appetite and also impedes mobility and quality of life. RA cannot be confirmed or excluded by one...

2009-04-06 03:24:00

MANILA, Philippines, April 6 /PRNewswire/ -- Rheumatoid arthritis (RA) is a systemic disease or an autoimmune disorder in which the body's defense system attacks the joints through the thin layer of cells called the synovium that lines and lubricates the joints. The most visible symptoms of RA are swollen joints and crippling stiffness, particularly of the hands and feet. It can cause fatigue, fever, loss of appetite and also impedes mobility and quality of life. In the Philippines, Serologic...

2009-03-31 22:40:00

KUALA LUMPUR, Malaysia, March 31 /PRNewswire/ -- Rheumatoid arthritis (RA) is a systemic disease or an autoimmune disorder in which the body's defense system attacks the joints through the thin layer of cells called the synovium that lines and lubricates the joints. The most visible symptoms of RA are swollen joints and crippling stiffness, particularly of the hands and feet. It can cause fatigue, fever, loss of appetite and also impedes mobility and quality of life. (Logo:...

2008-06-24 12:02:17

By de Seny, Dominique Fillet, Marianne; Ribbens, Clio; Maree, Raphael; Meuwis, Marie-Alice; Lutteri, Laurence; Chapelle, Jean-Paul; Wehenkel, Louis; Louis, Edouard; Merville, Marie-Paule; Malaise, Michel BACKGROUND: SELDI-TOF mass spectrometry (MS) is a high- throughput proteomic approach with potential for identifying novel forms of serum biomarkers of arthritis. METHODS: We used SELDI-TOF MS to analyze serum samples from patients with various forms of inflammatory arthritis. Several...

2008-06-16 09:01:19

Bristol-Myers Squibb has announced positive results from an exploratory Phase II study of 56 individuals that suggested that Orencia, a prescription drug for adults with moderate to severe rheumatoid arthritis, may delay the development of RA in people with undifferentiated inflammatory arthritis. In this small, randomized, double-blind, Phase II, multicenter, placebo-controlled, exploratory study, researchers investigated whether monotherapy with Orencia, administered for six months and...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.