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Latest Antimalarial drug Stories

2011-12-13 14:51:49

The largest ever study to assess the effects of malaria and its treatment in the first trimester of pregnancy has shown that the disease significantly increases the risk of miscarriage, but that treating with antimalarial drugs is relatively safe and reduces this risk. In the study, carried out at the Shoklo Malaria Research Unit (SMRU), in Thailand and funded by the Wellcome Trust, researchers examined medical records of women attending the unit's antenatal clinic over the 25 years since...

2011-12-12 17:45:35

The problems of archaic logistics infrastructure, inefficient distribution channels and disruptive black markets must all be addressed urgently if Africa is to cope with the growing problem of malaria, according to a study published in the International Journal of Logistics Systems and Management. Historically, malaria is humanity's biggest killer and although it has been eradicated in some regions it remains the biggest infectious threat in many parts of the world. Malaria kills 1.1...

2011-12-08 10:26:42

An antimalarial agent developed by researchers at Albert Einstein College of Medicine of Yeshiva University proved effective at clearing infections caused by the malaria parasite most lethal to humans — by literally starving the parasites to death. The novel research, carried out on a small number of non-human primates, could bolster efforts to develop more potent therapies against one of the world's leading killers. The study, published in the November 11, 2011 issue of PLoS ONE, was...

Breakthrough In The Battle Against Malaria
2011-11-30 05:54:45

Study identifies new ways to kill the human malaria parasite, Plasmodium falciparum An international team of scientists has announced a breakthrough in the fight against malaria, paving the way for the development of new drugs to treat the deadly disease. According to the World Health Organisation malaria currently infects more than 225 million people worldwide and accounts for nearly 800,000 deaths per year. Most deaths occur among children living in Africa where a child dies every 45...

2011-11-18 03:52:02

New class of compounds would target earliest stages of infection Researchers have discovered a group of chemical compounds that might one day be developed into drugs that can treat malaria infection in both the liver and the bloodstream. The study, which appears in the Nov. 18 issue of Science, was led by Elizabeth A. Winzeler, Ph.D., of the Scripps Research Institute in La Jolla, Calif., and was partially funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of...

2011-11-18 03:34:40

Findings point to the development of novel drugs that could eradicate the disease A international team led by scientists from the Genomics Institute of the Novartis Research Foundation (GNF) and The Scripps Research Institute has discovered a family of chemical compounds that could lead to a new generation of antimalarial drugs capable of not only alleviating symptoms but also preventing the deadly disease. In a study published November 17, 2011, in Science Express, the advance online...

2011-11-18 03:28:21

Data publicly available for global discovery The discovery of a new class of dual-acting antimalarial compounds - the imidazolopiperazines (IZPs) — was published in the journal Science online, at the Science Express website today1. The findings report on compounds that target both liver and blood infections, attacking the Plasmodium parasite at both stages in its reproduction cycle. The findings describe how scientists developed a novel assay to determine liver stage activity of...

2011-11-15 20:57:35

A study conducted by researchers at the Johns Hopkins Malaria Research Institute and their Zambian colleagues detected contrasting patterns of drug resistance in malaria-causing parasites taken from both humans and mosquitoes in rural Zambia. Parasites found in human blood samples showed a high prevalence for pyrimethamine-resistance, which was consistent with the class of drugs widely used to treat malaria in the region. However, parasites taken from mosquitoes themselves had very low...

2011-11-09 10:05:25

For some time now, artemisinin, derived from a Chinese herb, has been the most powerful treatment available against malaria. To avoid the malaria parasite becoming resistant, the World Health Organisation (WHO) strongly recommends combining artemisinin with another anti-malarial drug. But there are different formulations and derivatives, in different combinations and with dosing schemes. Scientists from the Institute of Tropical Medicine (ITM) carried out a head-to-head comparison of four...


Word of the Day
baudekin
  • A rich embroidered or brocaded silk fabric woven originally with a warp of gold thread.
'Baudekin' seems to be an alternative form of 'baldachin,' from the Italian 'Baldacco,' Baghdad, the city where the material was made.
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