Latest Antimalarial drug Stories
A large study from Africa, published in this week's PLoS Medicine, has found that in a direct comparison, three types of new, fast-acting antimalarial artemisinin-based combination therapy drugs (ACTs), which comprise artemisinin derivatives in combination with a partner antimalarial drug, AL (artesunate–mefloquine), ASAQ (artesunate–amodiaquine) and DHAPQ (dihydroartemisinin–piperaquine) are all effective for treating children with uncomplicated malaria.
Researchers at the University of South Florida (USF) College of Public College Health have shown for the first time in a rodent model that the earliest form of malaria parasites can lay dormant in red blood cells and “wake up,” or recover, following treatment with the antimalarial drug artesunate.
Researchers at the Perelman School of Medicine at the University of Pennsylvania, Monash University, and Virginia Tech have used a set of novel inhibitors to analyze how the malaria parasite, Plasmodium falciparum, uses enzymes to chew up human hemoglobin from host red blood cells as a food source.
Interventions targeting malaria, such as insecticide-treated bed nets, antimalarial drugs and mosquito control, could substantially reduce cases of bacteraemia, which kill hundreds of thousands of children each year in Africa and worldwide.
A novel technique to "tame" the malaria parasite, by forcing it to depend on an external supply of a vital chemical, has been developed by researchers at the Stanford University School of Medicine and the University of California-San Francisco.
Numerous potential anti-malarial candidate drugs have been uncovered by investigators from the National Institute of Allergy and Infectious Diseases (NIAID) and the National Human Genome Research Institute (NHGRI), both parts of the National Institutes of Health (NIH).
New research funded by the Wellcome Trust has shown that sending text message reminders to healthcare workers in rural Africa can improve the implementation of national guidelines for treating malaria.
When a person living in a malarial area gets a fever, health workers need to know the cause to make absolutely sure they give the right treatment.
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