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Latest Antimalarial drug Stories

2010-05-20 07:00:00

BURLINGAME, Calif., May 20 /PRNewswire/ -- GlaxoSmithKline (GSK) had teamed up with leading public-domain data providers European Bioinformatics Institute (EMBL-EBI), the U.S. National Library of Medicine (NLM) and the U.S.-based informatics service provider Collaborative Drug Discovery (CDD) to make freely available key scientific information on more than 13,500 compounds that could ultimately lead to new treatments for malaria. The release of this data marks the first time that a...

2010-05-19 12:00:00

MEMPHIS, Tenn., May 19 /PRNewswire/ -- An international team led by St. Jude Children's Research Hospital investigators today released data detailing the effectiveness of nearly 310,000 chemicals against a malaria parasite that remains one of the world's leading killers of young children. To view the multimedia assets associated with this release, please click: http://multivu.prnewswire.com/mnr/stjude/44038/ The research, which appears in the May 20 edition of the scientific journal...

2010-05-10 08:55:00

Amodiaquine was introduced as an antimalarial drug, but was withdrawn when serious adverse effects were observed. Scientists at the University of Gothenburg, Sweden, have now developed a method that can be used to develop safer drugs. A pharmaceutical in the body is, in the optimal case, broken down into harmless products (metabolites) that leave the body, for example via the urine. Some pharmaceuticals, however, can be converted into toxic products, which may result in serious adverse...

2010-03-29 15:15:00

SAN DIEGO, March 29 /PRNewswire/ -- Trius Therapeutics, Inc. today announced results from its Phase 1 clinical trial evaluating the safety, tolerability and pharmacokinetics of the intravenous (IV) dosage form of torezolid phosphate, an IV and orally administered second generation oxazolidinone for the treatment of serious gram positive infections, including methicillin-resistant Staphylococcus aureus (MRSA). The trial achieved its primary goal of establishing the safety and tolerability...

2010-02-16 14:57:53

International group of scientists publish critical discovery in Nature Genetics Scientists battling malaria have earned a major victory. According to a Nature Genetics study, an international group of researchers has used genomics to decode the blueprint of Plasmodium falciparum "“ a strain of malaria most resistant to drugs that causes the most deaths around the world. The discovery may lead to advanced pharmaceuticals to fight the disease and prevent drug resistance among the 250...

2010-02-09 16:23:37

Inadequacies may contribute to drug resistance The first results from a large-scale study of key antimalarial medicines in ten Sub-Saharan African countries reveal that a high percentage of medicines circulating on national markets are of substandard quality and thus may contribute to the growth of drug-resistant strains of Plasmodium falciparum, the most virulent form of malaria. The findings, released Feb. 8 by the Promoting the Quality of Medicines (PQM) Program, a USAID-funded program...

2010-02-08 08:00:00

Inadequacies May Contribute to Drug Resistance ROCKVILLE, Md., Feb. 8 /PRNewswire-USNewswire/ -- The first results from a large-scale study of key antimalarial medicines in ten Sub-Saharan African countries reveal that a high percentage of medicines circulating on national markets are of substandard quality and thus may contribute to the growth of drug-resistant strains of Plasmodium falciparum, the most virulent form of malaria. The findings, released today by the Promoting the Quality...

2010-02-05 15:20:37

This breakthrough makes NTU's School of Biological Sciences a global leader in transcriptional profiling of malaria -- and better yet, could lead to a cure for malaria Groundbreaking research done at Singapore's Nanyang Technological University's (NTU) School of Biological Sciences (SBS) could lead to the development of more potent drugs or a vaccine for malaria, which is transmitted to humans by infected mosquitoes and kills up to three million people each year. Assistant Professor Zbynek...

2010-02-03 22:20:51

Walter and Eliza Hall Institute researchers have identified a key protein used by the malaria parasite to transform human red blood cells, ensuring the parasite's survival. Their discovery means researchers have a clear target against which to develop a new class of anti-malarial drugs that destroy the parasite. Each year more than 400 million people contract malaria, and more than one million people, mostly children, die from the disease. The most lethal form of the disease is caused by the...

2010-01-29 13:59:25

Multinational team of researchers focuses on how parasites use enzymes to survive and spread disease Malaria causes more than two million deaths each year, but an expert multinational team battling the global spread of drug-resistant parasites has made a breakthrough in the search for better treatment. Better understanding of the make-up of these parasites and the way they reproduce has enabled an international team, led by John Dalton, a biochemist in McGill's Institute of Parasitology, to...


Word of the Day
holluschickie
  • A 'bachelor seal'; a young male seal which is prevented from mating by its herd's older males (mated bulls defending their territory).
This comes from the Russian word for 'bachelors.'
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