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Latest Apicomplexa Stories

2012-03-28 09:32:38

A three-arm randomized trial conducted by Ivo Mueller of the Papua New Guinea Institute of Medical Research, Madang, Papua New Guinea, and colleagues among infants in Papua New Guinea estimates the preventive effect against malaria episodes of intermittent preventive treatment, in an area where children are exposed to both falciparum and vivax malaria. Their findings, published in this week's PLoS Medicine, show that intermittent preventive treatment given during infancy at the time of...

2012-03-23 13:12:45

Researchers compare the genome of 2 parasites to explain differences in host range and transmission strategy Researchers have found the subtle genetic differences that make one parasite far more virulent than its close relative. They looked at the evolution of these parasites and found that although their genome architecture still remains similar, the two split from their common ancestor 28 million years ago, approximately four times longer than the human-gorilla split. Toxoplasma is...

2012-03-22 09:40:06

The parasite Toxoplasma gondii has some favorable effects on the pathogenesis and progression of a mouse model of Alzheimer's disease, reports a Mar. 21 study in the open access journal PLoS ONE. Toxoplasma gondii, a parasite commonly hosted in cats and generally known for the potential complications it can cause for human pregnancies, suppressed the immune system. The researchers behind today's study, led by Eun-Hee Shin of the Seoul National University College of Medicine, found that...

2012-02-28 21:51:51

A chemically altered osteoporosis drug may be useful in fighting malaria, researchers report in a new study. Unlike similar compounds tested against other parasitic protozoa, the drug readily crosses into the red blood cells of malaria-infected mice and kills the malaria parasite. The drug works at very low concentrations with no observed toxicity to the mouse. The researchers found the drug by screening a library of about 1,000 compounds used in previous efforts to target an important...

Mosquito Repellant Could Be Frightening For Mosquitoes!
2012-02-28 04:08:12

[ Watch the Video ] Repellant overwhelms their odor sensors, scaring them away In a small, narrow, temperature-controlled lab room at Vanderbilt University live some of the most deadly and dangerous animals in the world. "These are Anopheles mosquitoes that still think that they're in Central Africa. We won't tell them any different," says Laurence Zwiebel, professor of molecular biology and pharmacology. Anopheles gambiae mosquitoes can be killers. In warmer climates, the...

2012-02-23 18:00:54

Scientists have discovered a new target in their fight against the devastating global disease 'malaria' thanks to the discovery of a new protein involved in the parasite's life cycle. The research has uncovered a vital player in the sexual phase of the malaria parasite's reproduction which could prove an effective target for new treatments to stop the disease in its tracks. The scientists from The University of Nottingham's School of Biology, with collaborators from the Universities of...

2012-02-22 10:21:54

In this week's PLoS Medicine, Michael Delves of Imperial College London, UK and colleagues compare the activity of 50 current and experimental antimalarials against liver, sexual blood, and mosquito stages of selected human and nonhuman parasite species, including Plasmodium falciparum, Plasmodium berghei, and Plasmodium yoelii. These results provide a valuable guide to help researchers decide which drugs and compounds show most promise as potential future antimalarial drugs for blocking the...

2012-02-14 11:45:07

New research from the University of Melbourne shows how the malaria parasite (Plasmodium falciparum) changes into a banana shape before sexual reproduction, a finding that could provide targets for vaccine or drug development and may explain how the parasite evades the human immune system. The work was conducted by an Australian research team led by Dr Matthew Dixon and PhD student Megan Dearnley from the Department of Biochemistry and Molecular Biology, Bio21 Institute at the University...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
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