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Latest Apicomplexa Stories

2011-11-15 20:57:35

A study conducted by researchers at the Johns Hopkins Malaria Research Institute and their Zambian colleagues detected contrasting patterns of drug resistance in malaria-causing parasites taken from both humans and mosquitoes in rural Zambia. Parasites found in human blood samples showed a high prevalence for pyrimethamine-resistance, which was consistent with the class of drugs widely used to treat malaria in the region. However, parasites taken from mosquitoes themselves had very low...

Malaria Parasite Discovery May Lead To Vaccine
2011-11-10 14:08:10

[ Watch the Video ] Researchers have revealed a new discovery in understanding how a malaria parasite invades human red blood cells. The team from the Wellcome Trust Sanger Institute said they found that the parasite relies on a single receptor on the red blood cell's surface to invade. Malaria kills about a million people every year, most of them being children in Africa under the age of five. The blood stage of the parasite's lifecycle starts when it invades human red blood...

2011-11-09 10:05:25

For some time now, artemisinin, derived from a Chinese herb, has been the most powerful treatment available against malaria. To avoid the malaria parasite becoming resistant, the World Health Organisation (WHO) strongly recommends combining artemisinin with another anti-malarial drug. But there are different formulations and derivatives, in different combinations and with dosing schemes. Scientists from the Institute of Tropical Medicine (ITM) carried out a head-to-head comparison of four...

2011-11-09 09:59:16

A large study from Africa, published in this week's PLoS Medicine, has found that in a direct comparison, three types of new, fast-acting antimalarial artemisinin-based combination therapy drugs (ACTs), which comprise artemisinin derivatives in combination with a partner antimalarial drug, AL (artesunate—mefloquine), ASAQ (artesunate—amodiaquine) and DHAPQ (dihydroartemisinin—piperaquine) are all effective for treating children with uncomplicated malaria. In a randomized...

Image 1 - Which Came First? Humans Or Malaria?
2011-11-03 03:41:16

Malaria Revealed As Ancient, Adaptive And Persistent Foe One of the most comprehensive analyses yet done of the ancient history of insect-borne disease concludes for the first time that malaria is not only native to the New World, but it has been present long before humans existed and has evolved through birds and monkeys. The findings, presented in a recent issue of American Entomologist by researchers from Oregon State University, are based on the study of insect specimens preserved...

2011-11-01 15:17:14

A new research technology is revealing how humans develop immunity to malaria, and could assist programs aimed at eradicating this parasitic disease. Dr Alyssa Barry from the Walter and Eliza Hall Institute´s Infection and Immunity division is using ℠protein microarray´ technology to screen human blood serum samples for immunity to proteins produced by the malaria-causing Plasmodium falciparum parasite. Her research, which determines a person´s immunity to hundreds of...

2011-10-27 10:24:16

A new malaria vaccine could be the first to tackle different forms of the disease and help those most vulnerable to infection, a study suggests A new malaria vaccine could be the first to tackle different forms of the disease and help those most vulnerable to infection, a study suggests. The new vaccine is designed to trigger production of a range of antibodies to fight the many different types of parasite causing the disease. Scientists created the vaccine by combining multiple...

2011-10-27 10:21:20

Malaria is a major global health concern, and researchers are in need of new therapeutic approaches. To address this concern, a study published Oct. 26 in the online journal PLoS ONE reveals new information about the host cell's treatment of the parasite that causes the disease in mice, opening potential new avenues for research and treatment. The new work, led by Hernando del Portillo of the Barcelona Centre for International Health Research, used a mouse model of malaria infection to...


Word of the Day
virgule
  • A punctuation mark (/) used to separate related items of information.
  • A little rod; a twig.
This word comes from the Late Latin 'virgula,' accentual mark, a diminutive of 'virga,' rod.
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