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Last updated on April 18, 2014 at 21:21 EDT

Latest Apolipoprotein E Stories

2008-07-15 03:00:11

If the incidence of Alzheimer's continues to increase at the current rate more than 81 million people worldwide will be suffering from the disease by 2040. However, according to a recent study, the risk of developing the disease may be significantly reduced by a combination of vitamins E and C and ibuprofen. Feelgoodforlife.com provides additional information on which anti-aging supplements help Alzheimer's and other forms of dementia. The current study, as reported by Arkansasmatters.com,...

2008-06-26 06:00:00

By Delthia Ricks, Newsday, Melville, N.Y. Jun. 26--A gene that raises the risk of Alzheimer's disease by at least 45 percent, and possibly higher, has been identified by New York scientists and an international team of gene hunters. The discovery helps add context to what any layperson can see but what scientists have yet to fully explain: Most cases of Alzheimer's occur in people who are 65 and older. Until now, only one gene had been identified as a likely culprit -- ApoE4. Now,...

2008-06-26 00:00:20

A gene that raises the risk of Alzheimer's disease by at least 45 percent, and possibly higher, has been identified by New York scientists and an international team of gene hunters. The discovery helps add context to what any layperson can see but what scientists have yet to fully explain: Most cases of Alzheimer's occur in people who are 65 and older. Until now, only one gene had been identified as a likely culprit _ ApoE4. Now, Philippe Marambaud of the Feinstein Institute for Medical...

2008-06-18 12:01:00

U.S. researchers say they've found a protein that can predict Alzheimer's disease and the rate of progression of the human immunodeficiency virus. Investigators from The University of Texas Health Science Center at San Antonio led the study that provides more conclusive evidence of a link for the protein, called apoE4, to infectious diseases such as HIV. The scientists studied 1,300 European and African-American HIV-infected patients, comparing HIV clinical outcomes of individuals who...

2008-06-18 12:01:00

Elan and Wyeth have announced positive preliminary findings from a Phase II study of bapineuzumab in patients with mild to moderate Alzheimer's disease. In the 18-month trial, bapineuzumab appeared to have clinical activity in treating Alzheimer's disease. The study did not attain statistical significance on the primary efficacy endpoints in the overall study population. However, post-hoc analyses did show statistically significant and clinically meaningful benefits in important subgroups....

2008-06-18 12:00:11

The much anticipated results of a clinical trial of one of the more promising Alzheimer's drugs, released June 17, were mixed at best. But in the Alzheimer's world that qualifies as a success -- and on Wall Street, it was a winner as well. Wyeth Pharmaceuticals (WYE) and Elan Corp. (ELN) announced that the Phase II trial of their jointly developed drug, bapineuzumab, did not attain statistically significant results in the overall group of 240 patients. But in a subset of patients that...

2008-06-18 06:00:06

By Mary Brophy Marcus An experimental drug for Alzheimer's disease patients showed promise in Phase II clinical trials and is moving into final-stage trials, Wyeth and Elan, the makers of bapineuzumab, announced Tuesday. Bapineuzumab is designed to fight beta amyloid, a toxic protein that clumps together in the brains of Alzheimer's patients. In the early studies, conducted around the USA, 240 people with early- to moderate-stage Alzheimer's disease were either assigned bapineuzumab...

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2008-04-16 11:55:00

Heavy drinkers and heavy smokers develop Alzheimer's disease years earlier than people with Alzheimer's who do not drink or smoke heavily, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12"“19, 2008."These results are significant because it's possible that if we can reduce or eliminate heavy smoking and drinking, we could substantially delay the onset of Alzheimer's disease for people and reduce the...

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2008-03-11 00:05:00

Researchers at the University of Washington in Seattle reported Monday that a person's risk of Alzheimer's disease jumps dramatically if both parents have the disease. The researchers performed a study with 111 families in which both parents had been diagnosed with Alzheimer's disease, and then assessed the risk among the offspring of developing the disease. In total, the parents had 297 children, of whom 98 were at least 70 years old.  The research found that of these 98 children, 41,...

2006-07-18 07:21:18

WASHINGTON (Reuters) - The Alzheimer's drug Aricept not only improves memory and understanding in patients but appears to slow the characteristic shrinkage of the brain, researchers reported on Monday. Magnetic resonance imaging or MRI images of the brains of 131 patients with mild cognitive impairment showed less shrinkage of the hippocampus, a structure key to memory function, in patients who got the drug compared to those who got a placebo, researchers told a meeting. "No drug...