Latest Apolipoprotein E Stories
A new study shows that having a high amount of beta amyloid or "plaques" in the brain associated with Alzheimer's disease may cause steeper memory decline in mentally healthy older people than does having the APOE ɛ4 allele, also associated with the disease.
In one of two late-stage trials conducted by Pfizer, an experimental Alzheimer’s drug failed to slow the disease’s progress, but the pharma said on Monday that it will continue to study the drug’s effect on the other group.
A well-known genetic risk factor for Alzheimer’s disease triggers a cascade of signaling that ultimately results in leaky blood vessels in the brain, allowing toxic substances to pour into brain tissue in large amounts.
Common variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer's disease, but the gene's role in the disease has been unclear.
Efforts to understand how the aging process affects the brain and cognition have expanded beyond simply comparing younger and older adults.
- Growing in low tufty patches.