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Last updated on April 16, 2014 at 1:21 EDT

Latest Apolipoprotein E Stories

2011-12-12 17:30:02

If you had a family history of developing Alzheimer's disease, would you take a genetic test that would give you more information about your chances? "Definitely," said Gloria VanAlstine, 60, and Joyce Smith, 79. The two women took a controversial genetic test of a gene called Apolipoprotein E. APOE is a susceptibility gene where certain variants have been found to significantly increase a person's risk of developing Alzheimer's disease. Both women have a family history of Alzheimer's,...

2011-12-07 07:00:00

ST. LOUIS, Dec. 7, 2011 /PRNewswire/ -- Sigma-Aldrich® Corporation (Nasdaq: SIAL) today announced that Sigma Advanced Genetic Engineering (SAGE(TM)) Labs, an initiative of Sigma Life Science, has made available three genetically modified rat models that exhibit features key to studying conditions such as obesity, diabetes, atherosclerosis, high cholesterol, hypertension and familial hypercholesterolemia. Details on the models are available at...

Fish Consumption May Offer Critical Protection Against Alzheimer’s
2011-11-30 15:15:06

According to a recent study presented Wednesday at the annual meeting of the Radiological Society of North America (RSNA), scientists have uncovered yet another salubrious effect of consuming fish. This time, American researchers say that a recent study indicates that people who consume baked or grilled fish at least once a week are at a significantly lower risk of developing Alzheimer´s disease in old age. Not surprisingly, scientists say the explanation for fish´s protective...

2011-10-17 09:17:00

BROOMFIELD, Colo., Oct. 17, 2011 /PRNewswire/ -- Accera, Inc., a biotech company specializing in cognitive health, announced today that it has identified the genetic profile of Alzheimer's disease (AD) patients who have a high probability of responding to Axona® (AC-1202), a prescription medical food product available at pharmacies nationwide. In this current study, variances in the DNA sequences associated with the genes responsible for producing insulin degrading...

2011-08-24 09:00:00

NEW YORK, Aug. 24, 2011 /PRNewswire-USNewswire/ -- The Alzheimer's Drug Discovery Foundation (ADDF) announced that it has awarded a grant of $294,000 to Madera Biosciences, Inc. to develop small molecule drugs designed to clear accumulated beta-amyloid from the brain and thus halt or reverse the progression of Alzheimer's disease. Madera has identified a series of proprietary compounds that increase the expression of apolipoprotein E (apoE), which has been shown to mediate beta-amyloid...

2011-08-17 22:15:15

Researchers at Rhode Island Hospital's Alzheimer's Disease and Memory Disorders Center have found positive associations between fish oil supplements and cognitive functioning as well as differences in brain structure between users and non-users of fish oil supplements. The findings suggest possible benefits of fish oil supplements on brain health and aging. The results were reported at the recent International Conference on Alzheimer's Disease, in Paris, France. The study was led by Lori...

2011-07-20 00:30:00

PARIS, July 20, 2011 /PRNewswire-USNewswire/ -- Late breaking research results reported today at the Alzheimer's Association International Conference 2011 (AAIC 2011) in Paris include: Findings from a survey by Alzheimer Europe and the Harvard School of Public Health of experiences with and attitudes about Alzheimer's disease, especially regarding diagnosis, in France, Germany, Poland, Spain and the U.S. It reveals that while people fear Alzheimer's second only to cancer, the overwhelming...

2011-07-17 05:30:00

PARIS, July 17, 2011 /PRNewswire-USNewswire/ -- As the Alzheimer's field moves closer to new and earlier tests for the disease, innovative global research initiatives are taking the first important steps to standardize Alzheimer's biomarkers, as evidenced by two presentations made today at the Alzheimer's Association(R) International Conference 2011 (AAIC 2011) in Paris. One study compared, for the first time, results of brain amyloid imaging and the impact of genetics and ethnicity...

2011-05-13 11:03:48

What if you were told you carried a gene that increases your risk for Alzheimer's disease? And what if you were told this gene starts to do its damage not when you're old but when you're young? Brace yourself. Scientists know there is a strong genetic component to the development of late-onset Alzheimer's. In 1993, researchers discovered a gene known as ApoE4 "” carried by about a quarter of us "” that triples the risk for getting Alzheimer's. In 2009, three more risky genes were...

2011-05-10 14:01:25

The available evidence is insufficient to draw firm conclusions about the association of modifiable factors and risk of Alzheimer's disease (AD), according to a report posted online today that will appear in the September issue of Archives of Neurology, one of the JAMA/Archives journals. Estimates suggest that up to 5.3 million people in this country may have AD, and this number will likely increase as baby boomers grow older. In fact, "age is currently the strongest known risk factor for...