Quantcast

Latest Apolipoprotein E Stories

2011-07-17 05:30:00

PARIS, July 17, 2011 /PRNewswire-USNewswire/ -- As the Alzheimer's field moves closer to new and earlier tests for the disease, innovative global research initiatives are taking the first important steps to standardize Alzheimer's biomarkers, as evidenced by two presentations made today at the Alzheimer's Association(R) International Conference 2011 (AAIC 2011) in Paris. One study compared, for the first time, results of brain amyloid imaging and the impact of genetics and ethnicity...

2011-05-13 11:03:48

What if you were told you carried a gene that increases your risk for Alzheimer's disease? And what if you were told this gene starts to do its damage not when you're old but when you're young? Brace yourself. Scientists know there is a strong genetic component to the development of late-onset Alzheimer's. In 1993, researchers discovered a gene known as ApoE4 "” carried by about a quarter of us "” that triples the risk for getting Alzheimer's. In 2009, three more risky genes were...

2011-05-10 14:01:25

The available evidence is insufficient to draw firm conclusions about the association of modifiable factors and risk of Alzheimer's disease (AD), according to a report posted online today that will appear in the September issue of Archives of Neurology, one of the JAMA/Archives journals. Estimates suggest that up to 5.3 million people in this country may have AD, and this number will likely increase as baby boomers grow older. In fact, "age is currently the strongest known risk factor for...

2011-04-05 22:05:55

Higher levels in blood of the protein clusterin, also known as apolipoprotein J, are significantly associated with the prevalence and severity of Alzheimer's disease, but not with the risk of onset of new disease, according to a study in the April 6 issue of JAMA. Clusterin levels have been found to be increased in brain and cerebrospinal fluid of patients with Alzheimer disease (AD), and have been suggested to be involved in the pathogenesis of AD. "Plasma clusterin was reported to be...

369265bcf5a9a3a383165b483cca95171
2011-02-15 14:08:54

TAU says diets high in fish oil have a beneficial effect in patients at risk Scientists today agree that there are five molecules that are known to affect or cause Alzheimer's disease, which plagues an estimated five million Americans. The potency of these molecules is linked to environmental factors such as diet and lifestyle. Prof. Daniel Michaelson of Tel Aviv University's Department of Neurobiology at the George S. Wise Faculty of Life Sciences has illuminating news about one of these...

2011-01-19 18:42:27

The combined results of a genetic blood test and a five-minute functional MRI successfully classified more than three-quarters of healthy older adults, many of whom were destined to develop cognitive decline within 18 months of testing. John Woodard, Ph.D., associate professor of psychology in the College of Liberal Arts and Sciences and Institute of Gerontology at Wayne State University, is lead author of "Predicting Cognitive Decline in Healthy Older Adults Using fMRI" published in the...

2011-01-12 14:46:11

A Mayo Clinic researcher says the surprising findings suggest the possibility of a novel treatment for obesity A study by researchers at Mayo Clinic's campus in Florida and Washington University School of Medicine adds a new twist to the body of evidence suggesting human obesity is due in part to genetic factors. While studying hormone receptors in laboratory mice, neuroscientists identified a new molecular player responsible for the regulation of appetite and metabolism. In the Jan. 11...

2010-12-21 07:22:28

(Ivanhoe Newswire) "“ People at known high risk for Alzheimer's disease develop abnormal brain function even before the appearance of amyloid plaques that are characteristic of the disease. Scientists now can see the difference using an MRI scanner. The MRI revealed that these high risk patients had a particular form of the apolipoprotein E (APOE) gene called APOE4. The findings suggest that the gene variant affects brain function long before the brain begins to accumulate amyloid...

2010-12-16 14:54:06

APOE4 genotype linked to functional changes prior to formation of senile plaques People with a known, high risk for Alzheimer's disease develop abnormal brain function even before the appearance of telltale amyloid plaques that are characteristic of the disease, according to a new study. Researchers at Washington University School of Medicine in St. Louis report in the Dec. 15 issue of The Journal of Neuroscience that these patients had a particular form of the apolipoprotein E (APOE) gene...

2010-11-30 21:50:39

May have implications for the development of prevention therapies What are the earliest brain changes associated with the risk of developing Alzheimer's disease? A scientific report published in the October Journal of Alzheimer's Disease finds reduced activity of an energy-generating enzyme in deceased young adult brain donors who carry a common genetic risk factor for Alzheimer's disease"”before the protein changes or microscopic abnormalities commonly associated with the disease and...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.