Latest Apolipoprotein E Stories
HONOLULU, July 13 /PRNewswire-FirstCall/ -- Pfizer Inc.
By investigating the association between genetic loci related to Alzheimer's disease and neuroimaging measures related to disease risk, researchers may have uncovered additional evidence that several previously studied genetic variants are associated with the development and progression of Alzheimer's disease and also may have identified new genetic risk factors for further study.
A molecule implicated in Alzheimer's disease interferes with brain cells by making them unable to "recycle" the surface receptors that respond to incoming signals.
APOEe-4 gene carriers with Alzheimer's disease have more memory problems; non-carriers troubled with attention, language and executive function.
Although genome-wide analysis identified two genetic variations associated with Alzheimer disease (AD), these variations did not improve the ability to predict the risk of AD.
HOUSTON, April 21 /PRNewswire/ -- Effective immediately, SpectraCell Laboratories now offers apolipoprotein E genotyping.
PHOENIX, April 14 /PRNewswire/ -- A brain-imaging study published today in the Archives of Neurology suggests that a major genetic risk factor for Alzheimer's disease in the Anglo population is also a risk factor for the disease in Latinos. While a gene called APOE4 has been firmly established to increase an Anglo person's risk of Alzheimer's disease, its relationship to the disease in different Latino populations has been less clear.
Using sophisticated techniques that scan the genomes of patients, researchers at the Mayo Clinic campus in Florida have found that a gene appears to either help protect against development of Alzheimer's disease, or promote the disorder depending on the level of gene in the brain.
THESSALONIKI, Macedonia, Greece, March 9 /PRNewswire/ -- Accera, Inc., a biotechnology company delivering breakthrough therapies in central nervous system diseases, announced data which showed that augmentation with ketone bodies significantly improved cognitive function in Alzheimer's disease (AD) patients.
Researchers at Universitat AutÃ²noma de Barcelona (UAB) and University of Stockholm have created a computer modeling of the structural malfunctioning of the ApoE4 protein when it enters into contact with the Amyloid beta molecule, the main cause of Alzheimer's disease.
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