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Latest Apolipoprotein E Stories

2009-10-20 07:00:00

ST. LOUIS, Oct. 20 /PRNewswire-FirstCall/ -- Sigma-Aldrich® (Nasdaq: SIAL) today announced the launch of the SAGE(TM) Priority Partners Program, through which the Company plans to build a network of researchers to evaluate the 'knockout' rat models it is developing to support pre-clinical research work across a number of medical fields, including Neurobiology, Toxicology, Cardiology, Immunology and others. The partner program, managed by Sigma Advanced Genetic...

2009-10-06 14:27:11

The action of a small protein that is a major villain in Alzheimer's disease can be counterbalanced with another brain protein, researchers at UT Southwestern Medical Center have found in an animal study. The findings, available online in the journal Proceedings of the National Academy of Sciences, suggest a promising new tactic against the devastating illness, the researchers said. The harmful protein, called beta-amyloid, is found in the brain and, when functioning properly, suppresses...

2009-09-08 14:12:57

An international team of scientists led by Cardiff University in Wales has reported finding two more genetic risk factors of Alzheimer's disease. The group said it completed the largest genome-wide association study ever involving patients with Alzheimer's disease. The study pooled DNA samples from more than 19,000 older European and U.S. residents. The researchers said previously only four genes had been definitively associated with Alzheimer's disease -- three genetic mutations identified...

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2009-09-07 06:45:00

An international team of scientists has identified two more genetic risk factors for Alzheimer's disease. The findings are reported in the online edition of the journal Nature Genetics. The group, led by investigators from the School of Medicine at Cardiff in the United Kingdom and including scientists from Washington University School of Medicine in St. Louis, completed the largest genome-wide association study ever involving patients with Alzheimer's disease. The study pooled DNA samples...

2009-08-12 10:32:00

BROOMFIELD, Colo., Aug. 12 /PRNewswire/ -- Accera, Inc., a biotechnology company delivering breakthrough therapies in central nervous system (CNS) disorders, announced today publication of a scientific paper in the peer-reviewed journal Nutrition & Metabolism. The paper, entitled "Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial" suggests that daily administration of AC-1202 (Axona(TM)) can...

2009-07-16 08:36:48

 Researchers from Boston University School of Medicine (BUSM) have shown that disclosing genetic risk information to adult children of patients with Alzheimer's disease (AD) who request this information does not result in significant short-term psychological distress. The report from the REVEAL Study*, which appears in the July 16 issue of the New England Journal of Medicine, is the first randomized trial to disclose to participants whether or not they carried the ÃŽµ4...

2009-07-16 08:30:00

When people learn they are predisposed to Alzheimer's disease, any depression or anxiety is not long lasting, a new study indicates.These findings help address a longstanding debate about whether learning such information might cause lasting psychological harm, at least among those with a family history of Alzheimer's disease, says Scott Roberts, a University of Michigan researcher at the School of Public Health and co-author of the study findings, which appear today in the New England...

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2009-07-15 12:10:00

A large study of patients with mild cognitive impairment revealed that results from cognitive tests and brain scans can work as an early warning system for the subsequent development of Alzheimer's disease.The research found that among 85 participants in the study with mild cognitive impairment, those with low scores on a memory recall test and low glucose metabolism in particular brain regions, as detected through positron emission tomography (PET), had a 15-fold greater risk of developing...

2009-07-14 08:45:00

VIENNA, July 14 /PRNewswire-USNewswire/ -- Eating a "heart healthy" diet and maintaining or increasing participation in moderate physical activity may help preserve our memory and thinking abilities as we age, according to new research reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna. (Logo: http://www.newscom.com/cgi-bin/prnh/20090529/ICADLOGO ) "We can't do anything about aging or family history, but research...

2009-07-14 10:20:00

Eating a "heart healthy" diet and maintaining or increasing participation in moderate physical activity may help preserve our memory and thinking abilities as we age, according to new research reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna."We can't do anything about aging or family history, but research continues to show us that there are lifestyle decisions we all can make to keep our brains healthier, and that also...