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Last updated on April 19, 2014 at 13:20 EDT

Latest Apoptosis Stories

2012-04-30 14:51:23

Berkeley Lab scientists demonstrate the promise of synchrotron infrared spectroscopy of living cells for medical applications Knowing how a living cell works means knowing how the chemistry inside the cell changes as the functions of the cell change. Protein phosphorylation, for example, controls everything from cell proliferation to differentiation to metabolism to signaling, and even programmed cell death (apoptosis), in cells from bacteria to humans. It´s a chemical process that...

2012-04-30 14:37:30

St. Jude Children's Research Hospital discovery that a protein vital for cell survival and immune balance has another form with a different function could yield additional cancer treatment strategy Research led by St. Jude Children's Research Hospital investigators suggests that safeguarding cell survival and maintaining a balanced immune system is just the start of the myeloid cell leukemia sequence 1 (MCL1) protein's work. Nearly 20 years after MCL1 was discovered, scientists have...

2012-04-30 06:24:39

St. Jude Children's Research Hospital discovery that a protein vital for cell survival and immune balance has another form with a different function could yield additional cancer treatment strategy MEMPHIS, Tenn., April 30, 2012 /PRNewswire-USNewswire/ -- Research led by St. Jude Children's Research Hospital investigators suggests that safeguarding cell survival and maintaining a balanced immune system is just the start of the myeloid cell leukemia sequence 1 (MCL1) protein's...

2012-04-26 23:53:25

Ostrow School of Dentistry of USC study in Cell Stem Cell outlines the mechanism behind stem cells' beneficial effects on immune disorders A new study, appearing in Cell Stem Cell and led by researchers at the University of Southern California, outlines the specifics of how autoimmune disorders can be controlled by infusions of mesenchymal stem cells. Mesenchymal stem cells (MSC) are highly versatile stem cells that originate from the mesoderm, or middle layer of tissue, in a developing...

2012-04-24 02:25:52

TITUSVILLE, N.J., April 24, 2012 /PRNewswire/ -- Janssen Research & Development, LLC announced today the publication of an article that reviews the growing evidence that impaired mitochondrial function may play a major role in mood and psychotic disorders. The review discusses recent data from a wide array of human and animal studies that strongly support the theory that impaired mitochondrial function might disrupt neural plasticity pathways and reduce cellular...

2012-04-03 09:16:18

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma and primary effusion lymphoma (PEL). PELs are aggressive lymphomas with reported median survival time shorter than six months after diagnosis. Researchers at the University of Helsinki discovered that spontaneous induction of KSHV lytic replication in tumors drastically attenuated the p53-dependent apoptotic response not only to a targeted therapy (Nutlin-3) but also to genotoxic...

2012-03-29 02:26:09

SOUTH SAN FRANCISCO, Calif., March 29, 2012 /PRNewswire/ -- Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced the publication of an article in Cell, describing the crystal structures of two forms of the proteasome found in mammalian cells: the constitutive proteasome, expressed by the majority of cells in the body, and the immunoproteasome, expressed in cells derived from the bone marrow, including T-cells and B-cells, two types of white blood cells. In addition, this work includes...

2012-03-26 22:21:05

Team discovers mechanism for destroying particular cancer cells An international team of scientists has announced a new advance in the ability to target and destroy certain cancer cells. A group led by the University of Leicester has shown that particular cancer cells are especially sensitive to a protein called p21. This protein usually forces normal and cancer cells to stop dividing but it was recently shown that in some cases it can also kill cancer cells. However, scientists have...

2012-03-22 09:09:15

A new finding in basic science should trigger a "change in thinking" about how cancer drugs might be developed and tested for maximum effectiveness, says Louis M. Weiner, M.D., director of the Georgetown Lombardi Comprehensive Cancer Center, in a "Clinical Implications of Basic Research" article titled Tumor-Cell Death, Autophagy, and Immunity published in the March 22 issue of the New England Journal of Medicine (NEJM). An internationally known expert in immunotherapy research, Weiner was...