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Latest Apoptosis Stories

2011-12-12 16:16:33

An experimental drug that works by blocking the export of key control molecules from the nucleus of cancer cells shows promise as a treatment for chronic lymphocytic leukemia (CLL) and other incurable B-cell malignancies, according to a new study by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James). The agent, called KPT-SINE, belongs to a new class of drugs called...

2011-12-10 01:29:11

Suppressing a newly identified and characterized protein involved in regulating cell division could be a novel strategy to fight certain cancers because it stops the malignant cells from dividing and causes them to die quickly, according to a study by researchers with UCLA's Jonsson Comprehensive Cancer Center. During the five-year study, designed to seek new targets for anti-cancer therapies, researchers discovered that depleting the protein, called STARD9, also helped the commonly used...

2011-12-08 13:39:57

FINDINGS: A long non-coding RNA (lncRNA) prevents programmed cell death during one of the final stages of red blood cell differentiation, according to Whitehead Institute researchers. This is the first time a lncRNA has been found to play a role in red blood cell development and the first time a lncRNA has been shown to affect programmed cell death. RELEVANCE: Programmed cell death, or apoptosis, occurs in many cell development pathways; preventing normal cell death is a key step in the...

2011-11-08 15:18:16

Although Burkitt´s lymphoma is thankfully fairly rare in the general population, it is the most common form of malignancy in children in Equatorial Africa and is very frequent in immunocompromised persons, such as those suffering from AIDS.  It is invariably accompanied by an increase in the expression of a particular gene, the so-called c-myc gene.  An increased level of c-myc is not usually enough to cause cancer and most patients also have alterations to another gene. ...

2011-11-07 11:53:44

Discovery generates potential for new anti-cancer therapies Researchers at the University of Southern California have identified two molecules that may be more effective cancer killers than are currently available on the market. The peptides, molecules derived from a cancer-causing virus, target an enzyme in cancerous cells that regulates a widely researched tumor suppressor protein known as p53. The peptides inhibit the enzyme, causing p53 levels in cancer cells to rise, which leads to...


Word of the Day
pungle
  • To take pains; labor assiduously with little progress.
This word comes from the Spanish 'pongale,' put it.
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