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Latest Apoptosis Stories

2013-07-09 11:33:27

Knocking down cancer cell survival signals increases the effectiveness of chemotherapy Pancreatic cancer is one of the most deadly and intractable forms of cancer, with a 5-year survival rate of only 6%. Novel therapies are urgently needed, as conventional and targeted approaches have not been successful and drug resistance is an increasing problem. Previously it had been thought that poor penetration of the drugs into pancreas tumors was the main reason for treatment failure. But now a...

New Compound BH3 Mimetics Future Of Breast Cancer Treatment
2013-07-09 09:40:18

[ Watch the Video: New Anti-Cancer Compound Shows Promise For Breast Cancer ] Rebekah Eliason for redOrbit.com - Your Universe Online Scientists from Melbourne, Australia recently discovered compounds currently being researched to treat leukemia may also be effective in treating the most common form of breast cancer. Researchers found a group of anti-cancer compounds known as BH3-mimetics are effective for treating estrogen receptor-positive (ER-positive) forms of breast cancers when...

2013-06-24 11:32:01

A new study by a team of researchers from the University of Notre Dame provides an important new insight into how cancer cells are able to avoid the cell death process. The findings may suggest a chemotherapeutic approach to prevent the spread of cancers. Metastasis, the spread of cancer from one organ to other parts of the body, relies on cancer cells ability to evade a cell death process called anoikis, according to Zachary T. Schafer, Coleman Assistant Professor of Cancer Biology at...

2013-05-19 23:01:26

Australian Researchers Astonished to Learn P53 Not Only Seeks and Destroys, But Prevents DALLAS (PRWEB) May 19, 2013 Scientists are on the verge of unraveling the genesis of cancer. By studying the behavior of distorted genes in the malignant microenvironment (inside the body) studies are attempting to recode damaged gene signals so the body´s immune system can search and destroy cancer. But that´s not all. 1 P53 protein has long been the subject of intense investigation because...

2013-04-26 14:11:20

Proteins, unlike diamonds, aren't forever. And when they wear out, they need to be degraded in the cell back into amino acids, where they will be recycled into new proteins. Researchers at Rockefeller University and the Howard Hughes Medical Institute have identified a new way that the cell's protein recycler, the proteasome, takes care of unwanted and potentially toxic proteins, a finding that has implications for treating muscle wasting, neurodegeneration and cancer. The consensus among...

2013-04-25 20:23:59

New research reveals how the tumor suppressor p53 is shut down in metastatic melanoma -- and how it can be revived Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53. This protein stops potentially precancerous cells from dividing and induces suicide in those that are damaged beyond...

2013-04-23 12:06:30

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment.  They suggest that this is because p53 regulates the expression of two enzymes (JMJD2b and SUV39H1) that control the folding of DNA. According to the researchers, p53 is highly inducible by radiation. Activation of p53 stabilizes chromosomes by promoting the repair of heterochromatin DNA, which controls the expression of...

2013-04-17 17:24:41

A new, pre-clinical study by researchers at Virginia Commonwealth University Massey Cancer Center suggests that a novel drug combination could lead to profound leukemia cell death by disrupting the function of two major pro-survival proteins. The effectiveness of the therapy lies in its ability to target a pro-survival cell signaling pathway known as PI3K/AKT/mTOR, upon which the leukemia cells have become dependent. In the study, published in the journal Cancer Research, researchers...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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